Vindesine : Before Using - Eldisine®, desacetyl vinblastine amide sulfate, vincaleukoblastine

Vindesine - Systemic

Brand Names

Eldisine®, desacetyl vinblastine amide sulfate, vincaleukoblastine Vindesine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For vindesine, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to vindesine.

Pregnancy care

Vindesine has not been studied in pregnant women.

Before receiving vindesine make sure your family doctor knows if you are pregnant or if you may become pregnant. It is best to use some kind of birth control while you are receiving vindesine. Tell your family doctor right away if you think you have become pregnant while receiving vindesine.

Breast-feeding problem

It is not known whether vindesine passes into the breast milk. However, vindesine is not recommended during breast-feeding, because it may cause unwanted effects in nursing babies.

Use for Children

Although there is no special info comparing use of vindesine in child with use in other age groups, this drug is not expected to cause various side effects or problems in child than it does in adults.

Elderly care

Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no special info comparing use of vindesine in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking vindesine, it is especially important that your family doctor or pharmacist know if you are taking any of the following:

Acyclovir - Zovirax
Anticonvulsants - seizure drug
Antidiabetics, oral - diabetes drug taken by mouth
Anti-infectives by mouth or by injection - drug for infection
Antipsychotics - drug for mental illness
Captopril - Capoten
Carbamazepine - Tegretol
Enalapril - Vasotec
Flecainide - Tambocor
Gold salts - drug for arthritis
Imipenem
Inflammation or pain drug, except narcotics
Lisinopril - Prinivil, Zestril
Maprotiline - Ludiomil
Penicillamine - Cuprimine
Pimozide - Orap
Procainamide - Pronestyl
Promethazine - Phenergan
Ramipril - Altace
Sulfasalazine - Azulfidine
Tiopronin - Thiola
Tocainide - Tonocard
Tricyclic antidepressants - drug for depression
Trimeprazine - Temaril Concurrent use of these agents with vindesine may cause blood disorders

Alpha interferons - Intron A, Roferon-A
Amphotericin B by injection - Fungizone
Antineoplastics, other - cancer drug
Antithyroid agents - drug for overactive thyroid
Azathioprine - Imuran
Chloramphenicol - Chloromycetin
Colchicine
Cyclophosphamide - Cytoxan
Flucytosine - Ancoban
Ganciclovir - Cytovene
Mercaptopurine - Purinethol
Methotrexate - Rheumatrex
Plicamycin - Mithracin
Zidovudine - AZT, Retrovir Concurrent use of these agents with vindesine increases the risk of infection

Anti-infectives by mouth or by injection - drug for infection
Carbamazepine - Tegretol
Chloroquine - Aralen
Cisplatin - Platinol
Cytarabine - Cytosar-U
Diphtheria, tetanus and pertussis - DTP vaccine - recent, within 30 days of vindesine therapy
Disulfiram - Antabuse
Ethotoin - Peganone
Hydroxychloroquine - Plaquenil
Lindane, topical - Kwell
Lithium - Lithane
Mephenytoin - Mesantoin
Mexilitene - Mexitil
Pemoline - Cylert
Pyridoxine - Hexa-Betalin - with long-term, high-dose use
Quinine - Quinamm Concurrent use of these agents with vindesine increases the risk of neurotoxicity

Phenytoin - Dilantin Concurrent use of this agent with vindesine increases the risk of seizures

If you have ever been treated with radiation or cancer medication Vindesine may increase the side effects of medication or radiation therapy on the blood

Other Information for using

The presence of other medical problems may effect the use of vindesine. Make sure you tell your family doctor if you have any other medical problems, especially:

Charcot-Marie-Tooth syndrome, demyelinating form May cause increased neuropathic effects

Drug-induced blood disorders May worsen

Infection There may be an increased risk of infections or worsening infections because of the body's reduced ability to fight them

Chickenpox - including recent exposure
Herpes zoster - shingles chance of severe disease effecting other parts of the body

Liver disease Effects of vindesine may increase because of slower removal from the body

Nerve or muscle disease May worsen