Trimetrexate - tri-me-TREX-ate is using, together with leucovorin - loo-koe-VOR-in, to treat Pneumocystis carinii - - noo-moe-SISS-tis pneumonia - PCP, a very serious kind of pneumonia. This kind of pneumonia occurs commonly in diseaseds whose immune system is not working normally, such as cancer diseaseds, transplant diseaseds and diseaseds with acquired immune deficiency syndrome - AIDS.
Trimetrexate may cause some serious, even life-threatening, side effects. To prevent these effects, you must take another drug, leucovorin, together with trimetrexate and for 3 days after you stop receiving trimetrexate. Before you begin treat with trimetrexate, you and your family doctor must talk about the good this drug will do as well as the chance of using it.
Trimetrexate is to be aplaying only by or under the immediate supervision of your family doctor. It is available in the following dosage form:
Some commonly using brand names are:
In the USA
In Canada