Tamoxifen - Systemic
Brand Names
Nolvadex, Apo-Tamox, Gen-Tamoxifen, Nolvadex-D, Novo-Tamoxifen, PMS-Tamoxifen, Tamofen, Tamone
Tamoxifen *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For tamoxifen, the following
must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to tamoxifen.
Pregnancy care
Tell your family doctor if you are pregnant or if you intend
to become pregnant. Tamoxifen must not be using to reduce the risk of breast
cancer if you are pregnant of if you intend to become pregnant. Tamoxifen
use in women has been shown to cause miscarriages, birth defects, death of
the fetus and vaginal bleeding. Studies in rats and rabbits have shown that
tamoxifen causes miscarriages, death of the fetus and slowed learning. Studies
in pets also have shown that tamoxifen may cause some of the same problems
as those causing by an estrogen called diethylstilbestrol - DES. DES causes
genital tract problems and, rarely, an increased risk of cancer of the cervix
or vagina in daughters of women who took it during their pregnancy. It is
not known whether tamoxifen causes these same problems.Be sure that you have discussed this with your family doctor before taking this
drug. It is best to use some kind of birth control while you are taking
tamoxifen and for about 2 months after you stop taking it. However, do not
use oral contraceptives - “the Pill” since they may interfere
with this drug. Tell your family doctor right away if you think you have become
pregnant while taking tamoxifen.
Breast-feeding problem
Because this drug may cause serious side effects,
breast-feeding is generally not recommended while you are taking it.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. Although there is no special info
comparing use of tamoxifen in the elderly with use in other age groups, this
drug is not expected to cause various side effects or problems in older
people than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are taking any other prescription or nonprescription - over-the-counter
"OTC " drug. If you are taking tamoxifen to reduce the risk of breast
cancer, it is especially important that your health care professional know
if you are taking the following:
-
Anticoagulant, coumarin-type - blood thinners Blood thinners
- warfarin "Coumadin " must not be using with tamoxifen when using to
reduce the risk of developing breast cancer in women who have a high risk
of developing breast cancer. If you need to take blood thinners, your blood
clotting times must be monitored by your family doctor.
-
Cytotoxic medication These are medication that damage cells.
If you take these medication with tamoxifen, you may have an increased risk
of blood clots.
Other Information for using
The presence of other medical
problems may effect the use of tamoxifen. Make sure you tell your family doctor if
you have any other medical problems, especially:
For all diseaseds
-
Blood problems
-
Cataracts or other eye problems Tamoxifen may also cause these
problems
-
High cholesterol levels in the blood Tamoxifen can increase
cholesterol levels
When using for reducing the risk for developing breast cancer in high-risk
women or in women with Ductal Carcinoma in Situ - DCIS
-
Blood clots - or history of
-
Pulmonary embolism - or history of
-
Stroke
-
Uterine - womb cancer May increase risk of serious side effects
from tamoxifen.
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