Sulfasalazine - Systemic
Brand Names
Salazopyrin EN-Tabs, S.A.S.-500, S.A.S. Enteric-500, salazosulfapyridine, salicylazosulfapyridine, sulphasalazine, Azulfidine, Azulfidine EN-Tabs, Alti-Sulfasalazine, PMS-Sulfasalazine, PMS-Sulfasalazine E.C., Salazopyrin
Sulfasalazine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For sulfasalazine, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to any of the sulfa medication, furosemide - Lasix
or thiazide diuretics - water pills, oral antidiabetics - diabetes drug
you take by mouth, glaucoma drug you take by mouth - for example, acetazolamide
" Diamox ", dichlorphenamide " Daranide ", methazolamide " Neptazane ",
or salicylates - for example, aspirin. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy care
Sulfasalazine has not been studied in pregnant women.
However, reports on women who took sulfasalazine during pregnancy have not
shown that it causes birth defects or other problems. In addition, sulfasalazine
has not been shown to cause birth defects in studies in rats and rabbits given
doses of up to 6 times the human dose.
Breast-feeding problem
Sulfa medication pass into the breast milk in small
amounts and have been shown to cause unwanted effects in nursing babies with
glucose-6-phosphate dehydrogenase - G6PD deficiency. It may be necessary for
you to take another drug or to stop breast-feeding during treat. Be
sure you have discussed the chance and benefits of the drug with your family doctor.
Use for Children
Sulfasalazine must not be using in child up to
2 years of age because it may cause brain problems. However, sulfasalazine
has not been shown to cause various side effects or problems in child
over the age of 2 years than it does in adults.
Elderly care
This drug has been tested and has not been shown
to cause various side effects or problems in elderly people than it does in
adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
sulfasalazine, it is especially important that your health care professional
know if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Androgens - male hormones
-
Carbamazepine - Tegretol
-
Carmustine - BiCNU
-
Dantrolene - Dantrium
-
Daunorubicin - Cerubidine
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Estrogens - female hormones
-
Ethionamide - Trecator-SC
-
Etretinate - Tegison
-
Fat emulsions, intravenous - Intralipid - with prolonged use
-
Fluconazole - Diflucan
-
Gold salts - drug for arthritis
-
Inflammation or pain drug, except narcotics
-
Iron - with overdose
-
Labetalol - Normodyne
-
Lovastatin - Mevacor
-
Mercaptopurine - Purinethol
-
Methimazole - Tapazole
-
Naltrexone - ReVia - with long-term, high-dose use
-
Niacin - with high doses, sustained release and antihyperlipidemic
use
-
Nitrofurans
-
Other anti-infectives by mouth or by injection - drug for infection
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Plicamycin - Mithracin
-
Pravastatin - Pravachol
-
Propylthiouracil - Propyl-Thyracil
-
Simvastatin - Zocor
-
Troleandomycin
-
Valproic acid - Depakene or
-
Vitamin A - with chronic overdose Use of sulfasalazine with
these medication may increase the risk of side effects effecting the liver
-
Acetohydroxamic acid - Lithostat
-
Dapsone
-
Furazolidone - Furoxone
-
Menadiol - Synkavite
-
Nitrofurantoin - Furadantin
-
Primaquine
-
Procainamide - Pronestyl
-
Quinidine - Quinidex
-
Quinine - Quinamm
-
Sulfoxone - Diasone Use of sulfasalazine with these medication
may increase the risk of side effects effecting the blood
-
Anticoagulants - blood thinners
-
Ethotoin - Peganone
-
Mephenytoin - Mesantoin Use of sulfasalazine with these
medication may increase the risk of side side effects of medication
-
Antidiabetics, oral - diabetes drug you take by mouth Use
of oral antidiabetics with sulfasalazine may increase the risk of side effects
effecting the blood andincrease the side effects of oral antidiabetics
-
Methotrexate - Mexate Use of methotrexate with sulfasalazine
may increase the risk of side effects effecting the liver andincrease
the side effects of methotrexate
-
Methyldopa - Aldomet Use of methyldopa with sulfasalazine
may increase the risk of side effects effecting the liver andthe blood
-
Phenytoin - Dilantin Use of phenytoin with sulfasalazine
may increase the risk of side effects effecting the liver andincrease
the side effects of phenytoin
Other Information for using
The presence of other medical
problems may effect the use of sulfasalazine. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Allergies, severe
-
Asthma, bronchial The risk of an allergy to sulfasalazine
may be increased
-
Blood problems
-
Glucose-6-phosphate dehydrogenase deficiency - lack of G6PD enzyme Patients
with these problems may have an increase in side effects effecting the blood
-
Intestinal blockage Sulfasalazine will not reach the site of
action in the bowel
-
Kidney disease
-
Liver disease Patients with kidney disease or liver disease
may have an increased risk of side effects
-
Porphyria Use of sulfasalazine may cause an attack of porphyria
-
Urinary blockage Sulfasalazine may not be eliminated properly,
causing an increased risk of side effects
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