The best for you that your family doctor check your progress at regular appointments to make sure that this drug is help you and to check for unwanted effects.
While you are taking sirolimus, it is important to maintain good dental hygiene and see a dentist regularly for teeth cleaning.
Raw oysters or other shellfish may contain bacteria that can cause serious illness and possibly death. This is more likely to be a problem if these foods are eaten by diseaseds with certain medical conditions. Even eating oysters from “clean” water or good restaurants does not guarantee that the oysters do not contain the bacteria. Eating raw shellfish is not a problem for most healthy people; however, diseaseds with the following conditions may be at greater risk: cancer, immune disorders, organ transplantation, long-term corticosteroid use - as for asthma, arthritis, or organ transplantation, liver disease - including viral hepatitis, excess alcohol intake - 2 to 3 drinks or more per day, diabetes, stomach problems - including stomach surgery and low stomach acid and hemochromatosis - an iron disorder. Do not eat raw oysters or other shellfish while you are taking sirolimus. Be sure oysters and shellfish are fully cooked.
While you are being treated with sirolimus and after you stop treat with it, it is important to see your family doctor about the immunizations - vaccinations you must receive. Do not get any immunizations without your family doctor's approval. Sirolimus may lower your body's resistance and there is a risk you might get the infection the immunization is meant to prevent. In addition, other people living in your household must not take or have recently taken oral polio vaccine since there is a risk they could pass the polio virus on to you. Always avoid other people who have taken the oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you can't take these precautions, you must consider wearing a protective face mask that covers the nose and mouth.
Treatment with sirolimus may also increase the risk of getting other infections. If you can, avoid people with colds or other infections. If you think you are getting a cold or other infection, check with your family doctor.
Grapefruits and grapefruit juice may increase the effects of sirolimus by increasing the amount of this drug in your body You must not eat grapefruit or drink grapefruit juice while you taking this drug.