Saquinavir - Systemic
Brand Names
Fortovase, Invirase
Saquinavir *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For saquinavir, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to saquinavir. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy care
Studies have not been done. However, saquinavir
has not been reported to cause birth defects or other problems in animal studies.
Breast-feeding problem
It is not known whether saquinavir passes into
human breast milk. However, breast-feeding is usually not recommended in AIDS
diseaseds because of the risk of passing the AIDS virus on to the infant.
Use for Children
There is no special info comparing use of
saquinavir in child with use in other age groups.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. There is no special info comparing
use of saquinavir in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
saquinavir, it is especially important that your health care professional
know if you are taking any of the following:
-
Astemizole - Hismanal
-
Cisapride - Propulsid
-
Ergot medication - dihydroergotamine " D.H.E. 45 ", ergoloid mesylates
" Hydergine ", ergotamine " Ergotrate ", methylergonovine " Methergine ",
methysergide " Sansert "
-
Midazolam - Versed
-
Terfenadine - Seldane
-
Triazolam - Halcion There is a possibility that saquinavir
may interfere with the removal of these medication from the body, which could
lead to serious side effects
-
Calcium channel blocking agents - bepridil " Bepadin ", diltiazem
" Cardizem ", felodipine " Plendil ", flunarizine " Sibelium ",
isradipine " DynaCirc ", nicardipine " Cardene ", nifedipine "
Procardia ", nimodipine " Nimotop ", verapamil " Calan "
-
Quinidine - Quinidex There is a possibility that saquinavir
may interfere with the removal of these medication from the body, which could
lead to increased side effects
-
Carbamazepine - Tegretol
-
Dexamethasone - Decadron
-
Phenobarbital - Luminal
-
Phenytoin - Dilantin
-
Rifabutin - Mycobutin
-
Rifampin - Rifadin These medication may decrease the amount
of saquinavir in the body
-
Delavirdine - Rescriptor
-
Nevirapine - Viramune
-
Ritonavir - Norvir This drug may increase the amount
of saquinavir in the body, which could lead to increased side effects
Other Information for using
The presence of other medical
problems may effect the use of saquinavir. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Hemophilia Possible increased risk of bleeding
-
Liver disease Effects of saquinavir may be increased because
of slower removal of the drug from the body; also saquinavir has been
reported to cause unwanted effects on the liver
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