Salicylates - Systemic
Salicylates *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
If you are taking this drug
without a prescription, carefully read and follow any precautions on the label.
For salicylates, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to aspirin or other salicylates, including methyl salicylate
- oil of wintergreen, or to any of the following medication:
-
Diclofenac - Voltaren
-
Diflunisal - Dolobid
-
Etodolac - Lodine
-
Fenoprofen - Nalfon
-
Floctafenine - Idarac
-
Flurbiprofen, oral - Ansaid
-
Ibuprofen - Motrin
-
Indomethacin - Indocin
-
Ketoprofen - Orudis
-
Ketorolac - Toradol
-
Meclofenamate - Meclomen
-
Mefenamic acid - Ponstel
-
Nabumetone - Relafen
-
Naproxen - Naprosyn
-
Oxaprozin - Daypro
-
Oxyphenbutazone - Tandearil
-
Phenylbutazone - Butazolidin
-
Piroxicam - Feldene
-
Sulindac - Clinoril
-
Suprofen - Suprol
-
Tenoxicam - Mobiflex
-
Tiaprofenic acid - Surgam
-
Tolmetin - Tolectin
-
Zomepirac - Zomax
Also tell your health care professional if you are allergic to any other
substances, such as foods, preservatives, or dyes.
Diet Make certain your health care professional
knows if you are on a low-sodium diet. Regular use of large amounts of sodium
salicylate - as for arthritis can add a large amount of sodium to your diet.
Sodium salicylate contains 46 mg of sodium in each 325-mg tablet and 92 mg
of sodium in each 650-mg tablet.
Pregnancy care
Salicylates have not been shown to cause birth defects
in humans. Studies on birth defects have been done with aspirin
but not with other salicylates. However, salicylates causing birth defects
in animal studies.Some reports have suggested that too much use of aspirin late in pregnancy
may cause a decrease in the newborn's weight and possible death of the fetus
or newborn infant. However, the mothers in these reports had been taking much
larger amounts of aspirin than are usually recommended. Studies of mothers
taking aspirin in the doses that are usually recommended did not show these
unwanted effects. However, there is a risk that regular use of salicylates
late in pregnancy may cause unwanted effects on the heart or blood flow in
the fetus or in the newborn infant.
Use of salicylates, especially aspirin, during the last 2 weeks of pregnancy
may cause bleeding problems in the fetus before or during delivery or in the
newborn infant. Always too much use of salicylates during the last 3 months
of pregnancy may increase the length of pregnancy, prolong labor, cause other
problems during delivery, or cause severe bleeding in the mother before, during,
or after delivery
Do not take aspirin during the last
3 months of pregnancy unless it has been ordered by your family doctor
.
Studies have not shown that caffeine - present in some aspirin
products causes birth defects. However, studies in pets have shown that
caffeine causes birth defects when given in very large doses - amounts equal
to those present in 12 to 24 cups of coffee a day.
Breast-feeding problem
Salicylates pass into the breast milk. Although
salicylates have not been reported to cause problems in nursing babies, it
is possible that problems may occur if large amounts are taken regularly,
as for arthritis - rheumatism.Caffeine passes into the breast milk in small amounts.
Use for Children
Do not give aspirin or other
salicylates to a child or a teenager with a fever or other symptoms of a virus
infection, especially flu or chickenpox, without first discussing its use
with your child's family doctor
. This is very important because salicylates
may cause a serious illness called Reye's syndrome in child and teenagers
with fever causing by a virus infection, especially flu or chickenpox.Some children may need to take aspirin or another salicylate regularly
- as for arthritis. However, your child's family doctor may want to stop the drug
for a while if a fever or other symptoms of a virus infection occur. Discuss
this with your child's family doctor, so that you will know ahead of time what to
do if your child gets sick.
Children who do not have a virus infection may also be more sensitive to
the effects of salicylates, especially if they have a fever or have lost large
amounts of body fluid because of vomiting, diarrhea, or sweating. This may
increase the risk of side effects during treat.
Elderly care
Elderly people are especially sensitive to the effects
of salicylates. This may increase the risk of side effects during treat.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
a salicylate, it is especially important that your health care professional
know if you are taking any of the following:
-
Anticoagulants - blood thinners
-
Carbenicillin by injection - Geopen
-
Cefamandole - Mandol
-
Cefoperazone - Cefobid
-
Cefotetan - Cefotan
-
Dipyridamole - Persantine
-
Divalproex - Depakote
-
Heparin
-
Inflammation or pain drug, except narcotics,
-
Pentoxifylline - Trental
-
Plicamycin - Mithracin
-
Ticarcillin - Ticar
-
Valproic acid - Depakene Taking these medication together
with a salicylate, especially aspirin, may increase the risk of bleeding
-
Antidiabetics, oral - diabetes drug you take by mouth Salicylates
may increase the effects of the antidiabetic drug; a change in dose may
be needed if a salicylate is taken regularly
-
Ciprofloxacin - Cipro
-
Enoxacin - Penetrex
-
Itraconazole - Sporanox
-
Ketoconazole - Nizoral
-
Lomefloxacin - Maxaquin
-
Norfloxacin - Noroxin
-
Ofloxacin - Floxin
-
Tetracyclines - drug for infection, taken by mouth Buffered
aspirin, choline and magnesium salicylates and magnesium salicylate may keep
these medication from help you if taken too close to them
-
Methotrexate - Mexate
-
Vancomycin - Vancocin The risk of serious side effects
may be increased
-
Probenecid - Benemid Salicylates can keep probenecid
from help you for treating gout
-
Sulfinpyrazone - Anturane Salicylates can keep sulfinpyrazone
from help you for treating gout; also, taking a salicylate, especially
aspirin, with sulfinpyrazone may increase the risk of bleeding
-
Urinary alkalizers - drug that makes the urine less acid, such
as acetazolamide " Diamox ", calcium- andmagnesium-containing antacids,
dichlorphenamide " Daranide ", methazolamide " Neptazane ", potassium
or sodium citrate andcitric acid, sodium bicarbonate "baking soda " These
medication may make the salicylate less effective by causing it to be removed
from the body more quickly
Other Information for using
The presence of other medical
problems may effect the use of salicylates. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Anemia
-
Overactive thyroid
-
Stomach ulcer or other stomach problems Salicylates may make
your condition worse
-
Asthma, allergies and nasal polyps - history of
-
Glucose-6-phosphate dehydrogenase - G6PD deficiency
-
High blood pressure - hypertension
-
Kidney disease
-
Liver disease The risk of side effects may be increased.
-
Gout Salicylates can make this condition worse and can also
lessen the effects of some medication using to treat gout
-
Heart disease The risk of some side effects may be increased.
Always the caffeine present in some aspirin products can make some kinds of
heart disease worse
-
Hemophilia or other bleeding problems The risk of bleeding
may be increased, especially with aspirin
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