Rosiglitazone and Metformin - Systemic
Brand Names
Avandamet
Rosiglitazone and Metformin *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding
to use a drug, the chance of taking the drug must be weighed against
the good it will do. This is a decision you will make. For
rosiglitazone and metformin combination the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual
or allergy to rosiglitazone, metformin or any other ingredients
in the drug. Also tell your family doctor and pharmacist if you are allergic
to any other substances, such as foods, preservatives, or dyes.
Pregnancy care
Rosiglitazone and metformin combination has not
been studied in pregnant women or pets. It is easier during pregnancy to
control your blood sugar by using injections of insulin rather than by taking
oral diabetes medication. Close control of your blood sugar can reduce the
risk of your baby gaining too much weight, having birth defects, or having
high blood sugar before birth. Before taking this drug, make sure your
family doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding problem
It is not known whether rosiglitazone or metformin
passes into human breast milk. Although most medication pass into breast milk
in small amounts, many of them may be using safely while breast-feeding. Mothers
who are taking this drug and who wish to breast-feed must discuss this
with their family doctor.
Use for Children
Studies on this drug have been done only in
adult diseaseds and there is no special info comparing use of rosiglitazone
and metformin in child with use in other age groups.
Elderly care
Some older adults may be more sensitive than younger
adults to the side effects of medication. Older adults are more likely to
have age-related problems such as kidney problems. Rosiglitazone and metformin
must be using carefully as age increases and older adults may need a lower
dose of this drug.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
rosiglitazone and metformin, it is especially important that your family doctor and
pharmacist know if you are taking any of the following:
-
Alcohol Drinking alcohol may increase the risk of developing
lactic acidosis andvery low blood sugar.
-
Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol
" Tenoretic, Tenormin ", betaxolol " Kerlone ", Bisoprolol "
Zebeta, Ziac ", carteolol " Cartrol ", carvedilol " Coreg ", labetalol
" Normodyne ", metoprolol " Lopressor, Toprol ", nadolol " Corgard,
Corzide ", oxprenolol " Trasicor ", penbutolol " Levatol ", pindolol
" Visken ", propranolol " Inderal, Inderide ", sotalol " Betapace,
Sorine ", timolol " Blocadren, Timolide " Beta-adrenergic blocking
agents can hide the symptoms of low blood sugar - hypoglycemia. Because of
this, a person with diabetes might not recognize that he or she has low blood
sugar and might not take immediate steps to treat it.
-
Amiloride - Midamor
-
Cimetidine - Tagamet
-
Digoxin - Lanoxin
-
Morphine - MS Contin
-
Procainamide - Procanbid, Pronestyl
-
Quinidine - Quinaglute, Quinidex
-
Quinine - malaria drug
-
Ranitidine - Zantac
-
Triamterene - Dyrenium
-
Trimethoprim - Proloprim
-
Vancomycin - Vancocin Using these medication with rosiglitazone
and metformin may cause there to be too much rosiglitazone and metformin in
your body. This may increase the risk of low blood sugar or other side effects.
-
Furosemide - Lasix Using this drug with rosiglitazone
and metformin may cause there to be too much metformin in your body and a
lower dose of rosiglitazone and metformin may be needed.
Other Information for using
The presence
of other medical problems may effect the use of rosiglitazone and metformin
. Make sure you tell your family doctor if you have any other medical problems, especially:
-
Adrenal glands, not properly controlled
-
Alcohol intoxication
-
Caloric intake, deficient - not enough calories
-
Elderly diseaseds
-
Undernourished condition
-
Underactive pituitary gland, not properly controlled
-
Any other condition that causes low blood sugar Patients with
these conditions may be more likely to develop low blood sugar while taking
a medication that contains rosiglitazone and metformin.
-
Dehydration - not enough water in your body
-
Heart attack
-
Sepsis - serious illness due to a bacterial infection
-
Shock These conditions can cause serious problems; if they
happen you must stop taking this drug as soon as possible
-
Diabetic ketoacidosis - ketones in the blood
-
Lactic acidosis - lactic acid in the blood
-
Metabolic acidosis - extra acids in the blood Patients with
any of these conditions must not use this drug
-
Edema Patients with this condition must use this drug
with caution; use of this drug can increase the risk of serious side effects
in these diseaseds
-
Fever
-
Infection
-
Surgery
-
Trauma These conditions may cause temporary problems with
blood sugar control and your healthcare professional may want to treat you
temporarily with insulin.
-
Heart failure, congestive Patients with this condition must
not use this drug.
-
Jaundice Patients with this condition must use this drug
with caution; use of this drug can increase the risk of serious side effects
in these diseaseds.
-
Kidney disease Patients with this condition must not use
this drug
-
Kidney, heart, or other problems that require medical tests or examinations
that use certain medication called contrast agents, with x-ray exams Because
this drug contains metformin, your family doctor must advise you to stop taking
it before you have any medical exams or diagnostic tests that might cause
less urine output than usual; you may be advised to start taking the drug
again 48 hours after the exams or tests if your kidney function is tested
and found to be normal.
-
Liver function, impaired Patients with impaired liver condition
generally must not use this drug
-
Surgery Use of this drug must be suspended during surgical
procedures - except for minor surgical procedures; you can take your drug
again after your healthcare professional makes sure your kidneys are normal
-
Type 1 diabetes Patients with this condition must not use
this drug
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