Rosiglitazone and Metformin : Before Using

Rosiglitazone and Metformin - Systemic

Brand Names

Avandamet Rosiglitazone and Metformin *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to use a drug, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For rosiglitazone and metformin combination the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to rosiglitazone, metformin or any other ingredients in the drug. Also tell your family doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

Rosiglitazone and metformin combination has not been studied in pregnant women or pets. It is easier during pregnancy to control your blood sugar by using injections of insulin rather than by taking oral diabetes medication. Close control of your blood sugar can reduce the risk of your baby gaining too much weight, having birth defects, or having high blood sugar before birth. Before taking this drug, make sure your family doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding problem

It is not known whether rosiglitazone or metformin passes into human breast milk. Although most medication pass into breast milk in small amounts, many of them may be using safely while breast-feeding. Mothers who are taking this drug and who wish to breast-feed must discuss this with their family doctor.

Use for Children

Studies on this drug have been done only in adult diseaseds and there is no special info comparing use of rosiglitazone and metformin in child with use in other age groups.

Elderly care

Some older adults may be more sensitive than younger adults to the side effects of medication. Older adults are more likely to have age-related problems such as kidney problems. Rosiglitazone and metformin must be using carefully as age increases and older adults may need a lower dose of this drug.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking rosiglitazone and metformin, it is especially important that your family doctor and pharmacist know if you are taking any of the following:

Alcohol Drinking alcohol may increase the risk of developing lactic acidosis andvery low blood sugar.

Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol " Tenoretic, Tenormin ", betaxolol " Kerlone ", Bisoprolol " Zebeta, Ziac ", carteolol " Cartrol ", carvedilol " Coreg ", labetalol " Normodyne ", metoprolol " Lopressor, Toprol ", nadolol " Corgard, Corzide ", oxprenolol " Trasicor ", penbutolol " Levatol ", pindolol " Visken ", propranolol " Inderal, Inderide ", sotalol " Betapace, Sorine ", timolol " Blocadren, Timolide " Beta-adrenergic blocking agents can hide the symptoms of low blood sugar - hypoglycemia. Because of this, a person with diabetes might not recognize that he or she has low blood sugar and might not take immediate steps to treat it.

Amiloride - Midamor
Cimetidine - Tagamet
Digoxin - Lanoxin
Morphine - MS Contin
Procainamide - Procanbid, Pronestyl
Quinidine - Quinaglute, Quinidex
Quinine - malaria drug
Ranitidine - Zantac
Triamterene - Dyrenium
Trimethoprim - Proloprim
Vancomycin - Vancocin Using these medication with rosiglitazone and metformin may cause there to be too much rosiglitazone and metformin in your body. This may increase the risk of low blood sugar or other side effects.

Furosemide - Lasix Using this drug with rosiglitazone and metformin may cause there to be too much metformin in your body and a lower dose of rosiglitazone and metformin may be needed.

Other Information for using

The presence of other medical problems may effect the use of rosiglitazone and metformin . Make sure you tell your family doctor if you have any other medical problems, especially:

Adrenal glands, not properly controlled
Alcohol intoxication
Caloric intake, deficient - not enough calories
Elderly diseaseds
Undernourished condition
Underactive pituitary gland, not properly controlled
Any other condition that causes low blood sugar Patients with these conditions may be more likely to develop low blood sugar while taking a medication that contains rosiglitazone and metformin.

Dehydration - not enough water in your body
Heart attack
Sepsis - serious illness due to a bacterial infection
Shock These conditions can cause serious problems; if they happen you must stop taking this drug as soon as possible

Diabetic ketoacidosis - ketones in the blood
Lactic acidosis - lactic acid in the blood
Metabolic acidosis - extra acids in the blood Patients with any of these conditions must not use this drug

Edema Patients with this condition must use this drug with caution; use of this drug can increase the risk of serious side effects in these diseaseds

Fever
Infection
Surgery
Trauma These conditions may cause temporary problems with blood sugar control and your healthcare professional may want to treat you temporarily with insulin.

Heart failure, congestive Patients with this condition must not use this drug.

Jaundice Patients with this condition must use this drug with caution; use of this drug can increase the risk of serious side effects in these diseaseds.

Kidney disease Patients with this condition must not use this drug

Kidney, heart, or other problems that require medical tests or examinations that use certain medication called contrast agents, with x-ray exams Because this drug contains metformin, your family doctor must advise you to stop taking it before you have any medical exams or diagnostic tests that might cause less urine output than usual; you may be advised to start taking the drug again 48 hours after the exams or tests if your kidney function is tested and found to be normal.

Liver function, impaired Patients with impaired liver condition generally must not use this drug

Surgery Use of this drug must be suspended during surgical procedures - except for minor surgical procedures; you can take your drug again after your healthcare professional makes sure your kidneys are normal

Type 1 diabetes Patients with this condition must not use this drug