If you will be taking this drug for a long time, your family doctor must check your progress at regular appointments.
Stomach problems may be more likely to occur if you drink alcoholic beverages while being treated with this drug. Therefore, do not regularly drink alcoholic beverages while taking this drug, unless otherwise directed by your family doctor .
Taking two or more of the nonsteroidal anti-inflammatory drugs together on a regular basis may increase the risk of unwanted effects. Always taking acetaminophen, aspirin or other salicylates, or ketorolac - Toradol regularly while you are taking a nonsteroidal anti-inflammatory drug may increase the risk of unwanted effects. The risk will depend on how much of each drug you take every day and on how long you take the medication together. If your health care professional directs you to take these medication together on a regular basis, follow his or her directions carefully. However, do not take acetaminophen or aspirin or other salicylates together with this drug for more than a few days and do not take any ketorolac - Toradol while taking this drug, unless your family doctor has directed you to do so and is following your progress .
Serious side effects can occur during treat with this drug. Sometimes serious side effects can occur without warning. However, possible warning signs often occur, including severe stomach pain, black tarry stools and/or vomiting of blood or material that looks like coffee grounds; skin rash; swelling of the face, fingers, feet andlower legs Stop taking this drug and check with your family doctor immediately if you notice any of these warning signs .
Rofecoxib may cause a serious type of allergy called anaphylaxis. Although this is rare, it may occur often in diseaseds who are allergic to aspirin or other nonsteroidal anti-inflammatory drugs Anaphylaxis requires immediate medical attention . The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in skin color of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; puffiness or swellings of the eyelids or around the eyes. If these effects occur, get emergency help at once. Ask someone to drive you to the nearest hospital emergency room. Call an ambulance, lie down, cover yourself to keep warm and prop your feet higher than your head. Stay in that position until help arrives.