Rifampin - Systemic
Brand Names
Rifadin, Rifadin IV, Rimactane, Rofact, rifampicin
Rifampin *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For rifampin, the following
must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to rifampin. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy care
Pregnant women with tuberculosis - TB must be treated
with TB medication, including rifampin. Rifampin can rarely cause bleeding
in newborn babies and mothers when taken during the last weeks of pregnancy.
Studies in rats and mice have shown that rifampin given in high doses causes
birth defects, usually backbone problems - spina bifida and cleft palate.
Breast-feeding problem
Rifampin passes into the breast milk. However,
rifampin has not been reported to cause problems in nursing babies.
Use for Children
This drug has been tested in child and, in
effective doses, has not been shown to cause various side effects or problems
in child than it does in adults.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. Although there is no special info
comparing use of rifampin in the elderly with use in other age groups, this
drug is not expected to cause various side effects or problems in older
people than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
rifampin, it is especially important that your health care professional know
if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Androgens - male hormones
-
Antithyroid agents - drug for overactive thyroid
-
Carbamazepine - Tegretol
-
Carmustine - BiCNU
-
Chloroquine - Aralen
-
Dantrolene - Dantrium
-
Daunorubicin - Cerubidine
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Etretinate - Tegison
-
Gold salts - drug for arthritis
-
Hydroxychloroquine - Plaquenil
-
Isoniazid - INH, Nydrazid
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Methyldopa - Aldomet
-
Naltrexone - Trexan - with long-term, high-dose use
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Plicamycin - Mithracin
-
Valproic acid - Depakene These medication may increase
the risk of liver damage if taken with rifampin
-
Anticoagulants - blood thinners
-
Aminophylline - Somophyllin
-
Amprenavir - e.g. Agenerase
-
Antidiabetics, oral - diabetes drug you take by mouth,
-
Chloramphenicol
-
Corticosteroids - cortisone-like drug
-
Delavirdine - Rescriptor
-
Digitalis glycosides - heart drug
-
Disopyramide - Norpace
-
Efavirenz - Sustiva
-
Fluconazole - Diflucan
-
Indinavir - Crixivan
-
Itraconazole - Sporanox
-
Ketoconazole - Nizoral
-
Methadone - Dolophine
-
Mexiletine - Mexitil
-
Nelfinavir - Viracept
-
Nevirapine - Viramune
-
Oxtriphylline - Choledyl
-
Quinidine - Quinidex
-
Ritonavir - Norvir
-
Saquinavir - Fortovase, Invirase
-
Theophylline - Theo-Dur, Somophyllin-T
-
Tocainide - Tonocard
-
Verapamil - Calan Rifampin may decrease the effects of
these medication
-
Estramustine - EMCYT
-
Estrogens - female hormones
-
Oral contraceptives - birth control pills containing estrogen
-
Phenytoin - Dilantin Rifampin may decrease the effects
of these medication. If you are taking oral contraceptives, this may increase
the risk of pregnancy. These medication may also increase the risk of liver
damage if taken with rifampin
Other Information for using
The presence of other medical
problems may effect the use of rifampin. Make sure you tell your family doctor if
you have any other medical problems, especially:
-
Alcohol abuse - or history of
-
Liver disease There may be an increased risk of side effects
effecting the liver in diseaseds with a history of alcohol abuse or liver disease
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