Prescription drugs 
  



Rifampin, Isoniazid and Pyrazinamide - Systemic

Brand Names

Rifater
Rifampin, Isoniazid and Pyrazinamide *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For rifampin, isoniazid, and pyrazinamide combination, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to ethionamide - Trecator-SC, pyrazinamide, niacin - Nicobid, nicotinic acid, rifampin - Rifadin, rifabutin - Mycobutin, or isoniazid - INH, Nydrazid. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

Pregnant women with tuberculosis - TB must be treated with TB medication, including isoniazid, pyrazinamide and rifampin. Rifampin, isoniazid and pyrazinamide combination has not been shown to cause birth defects or other problems. However, rifampin can rarely cause bleeding in newborn babies and mothers when taken during the last weeks of pregnancy. Always studies in rats and mice have shown that rifampin given in high doses causes birth defects, usually backbone problems - spina bifida and cleft palate.

Breast-feeding problem

Rifampin, isoniazid and pyrazinamide pass into the breast milk. However, rifampin, isoniazid and pyrazinamide have not been reported to cause problems in nursing babies.

Use for Children

Rifampin, isoniazid and pyrazinamide combination may not be appropriate for use in child and adolescents up to 15 years of age.

Elderly care

Liver problems are more likely to occur in diseaseds over 50 years of age who are taking isoniazid-containing medication.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking rifampin, isoniazid and pyrazinamide combination, it is especially important that your health care professional know if you are taking any of the following:

Other Information for using

The presence of other medical problems may effect the use of rifampin, isoniazid and pyrazinamide combination. Make sure you tell your family doctor if you have any other medical problems, especially: 








  

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