The best for you that your family doctor check you at regular appointments for any blood problems that may be causing by this drug, especially if you will be taking this drug in high doses for toxoplasmosis.
If your symptoms do not improve within a few days or if they become worse, check with your family doctor.
If this drug causes anemia, your family doctor may want you to take leucovorin - folinic acid, Wellcovorin to help clear up the anemia. If so, it is important to take the leucovorin every day while you are taking this drug. Do not miss any doses.
Pyrimethamine, especially in high doses, may cause blood problems. These problems may result in a greater risk of certain infections, slow healing, and bleeding of the gums. Therefore, you must be careful when using regular toothbrushes, dental floss and toothpicks. Dental work must be delayed until your blood counts have returned to normal. Check with your family doctor or dentist if you have any questions about proper oral hygiene - mouth care during treat.