Brand Names

How to Use

If probenecid upsets your stomach, it may be taken with food. If this does not work, an antacid may be taken. If stomach upset - nausea, vomiting, or loss of appetite continues, check with your family doctor.

For diseaseds taking probenecid for gout :

• After you begin to take probenecid, gout attacks may continue to occur for a while. However, if you take this drug regularly as directed by your family doctor, the attacks will gradually become less frequent and less painful than before. After you have been taking probenecid for few months, they may stop completely.
• This drug will help prevent gout attacks but it will not relieve an attack that has already started Even if you take another drug for gout attacks, continue to take this drug also . If you have any questions about this, check with your family doctor.

For diseaseds taking probenecid for gout or to help remove uric acid from the body :

• When you first begin taking probenecid, the amount of uric acid in the kidneys is greatly increased. This may cause kidney stones or other kidney problems in some people. To help prevent this, your family doctor may want you to drink at least 10 to 12 full glasses - 8 ounces each of fluids each day, or to take another drug to make your urine less acid. It is important that you follow your family doctor's instructions very carefully.

Dosage

• For treating gout or removing uric acid from the body :
  • Adults: 250 mg - one-half of a 500-mg tablet two times a day for about one week, then 500 mg - one tablet two times a day for a few weeks. After this, the dose will depend on the amount of uric acid in your blood or urine. Most people need 2, 3, or 4 tablets a day, but some people may need higher doses.
  • Children: It is not likely that probenecid will be needed to treat gout or to remove uric acid from the body in child. If a child needs this drug, however, the dose would have to be determined by the family doctor.
• For helping antibiotics work better :
  • Adults: The amount of probenecid will depend on the condition being treated. Sometimes, only one dose of 2 tablets is needed. Other times, the dose will be 1 tablet four times a day.
  • Children: The dose will have to be determined by the family doctor. It depends on the child's weight, as well as on the condition being treated. Older children and teenagers may need the same amount as adults.

Missed dose If you are taking probenecid regularly and you miss a dose, take the missed dose as soon as possible. However, if you do not remember until it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage To store this drug:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store this drug in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the drug to break down.
• Do not keep outdated drug or drug no longer needed. Be sure that any discarded drug is out of the reach of children.