Penicillins - Systemic
Penicillins *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For penicillins, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to any of the penicillins or cephalosporins. Also tell your
health care professional if you are allergic to any other substances, such
as foods, preservatives, or dyes, or procaine - Novocain or other ester-type
anesthetics - medication that cause numbing if you are receiving penicillin
G procaine.
Diet Make certain your health care professional
knows if you are on a low-sodium - low-salt diet. Some of these medication
contain enough sodium to cause problems in some people.
Pregnancy care
Penicillins have not been studied in pregnant women.
However, penicillins have been widely using in pregnant women and have not
been shown to cause birth defects or other problems in animal studies.
Breast-feeding problem
Penicillins pass into the breast milk. Even though
only small amounts may pass into breast milk, allergys, diarrhea,
fungus infections and skin rash may occur in nursing babies.
Use for Children
Many penicillins have been using in child and,
in effective doses, are not expected to cause various side effects or problems
in child than they do in adults.Some strengths of the chewable tablets of amoxicillin contain aspartame,
which is changed by the body to phenylalanine, a substance that is harmful
to diseaseds with phenylketonuria.
Elderly care
Penicillins have been using in the elderly and have
not been shown to cause various side effects or problems in elderly people
than they do in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
a penicillin, it is especially important that your health care professional
know if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Androgens - male hormones
-
Antithyroid agents - drug for overactive thyroid
-
Carmustine - BiCNU
-
Chloroquine - Aralen
-
Dantrolene - Dantrium
-
Daunorubicin - Cerubidine
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Estrogens - female hormones
-
Etretinate - Tegison
-
Gold salts - drug for arthritis
-
Hydroxychloroquine - Plaquenil
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Methyldopa - Aldomet
-
Naltrexone - Trexan - with long-term, high-dose use
-
Oral contraceptives - birth control pills containing estrogen
-
Other anti-infectives by mouth or by injection - drug for infection
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Plicamycin - Mithracin
-
Valproic acid - Depakene These medication may increase
the risk of liver damage if taken with cloxacillin, dicloxacillin, flucloxacillin,
mezlocillin, nafcillin, oxacillin, or piperacillin
-
Amiloride - Midamor
-
Benazepril - Lotensin
-
Captopril - Capoten
-
Enalapril - Vasotec
-
Fosinopril - Monopril
-
Lisinopril - Prinivil, Zestril
-
Potassium-containing drug
-
Quinapril - Accupril
-
Ramipril - Altace
-
Spironolactone - Aldactone
-
Triamterene - Dyrenium Use of these medication with penicillin
G by injection may cause an increase in side effects
-
Anticoagulants - blood thinners
-
Dipyridamole - Persantine
-
Divalproex - Depakote
-
Heparin - Panheprin
-
Inflammation or pain drug - except narcotics
-
Pentoxifylline - Trental
-
Plicamycin - Mithracin
-
Sulfinpyrazone - Anturane
-
Valproic acid - Depakene Use of these medication with
high doses of carbenicillin, piperacillin, or ticarcillin may increase the
risk of bleeding
-
Chloramphenicol - Chloromycetin
-
Erythromycins - E.E.S., E-Mycin, ERYC
-
Sulfonamides - Gantanol, Gantrisin
-
Tetracyclines - Achromycin, Minocin, Vibramycin Use of
these medication with penicillins may prevent the penicillin from help you
-
Cholestyramine - Questran
-
Colestipol - Colestid Use of these medication with oral
penicillin G may prevent penicillin G from help you
-
Oral contraceptives - birth control pills containing estrogen Use
of ampicillin, amoxicillin, or penicillin V with estrogen-containing oral
contraceptives may prevent oral contraceptives from help you, increasing
the risk of pregnancy
-
Methotrexate - Mexate Use of methotrexate with penicillins
may increase the risk of side effects of methotrexate
-
Probenecid - Benemid Probenecid causes penicillins to
build up in the blood. This may increase the risk of side effects. However,
your family doctor may want to give you probenecid with a penicillin to treat some
infections
Other Information for using
The presence of other medical
problems may effect the use of penicillins. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Allergy, general - such as asthma, eczema, hay fever, hives, history
of Patients with a history of general allergies may be more likely to
have a severe reaction to penicillins
-
Bleeding problems, history of Patients with a history of bleeding
problems may be more likely to have bleeding when receiving carbenicillin,
piperacillin, or ticarcillin
-
Congestive heart failure - CHF
-
High blood pressure Large doses of carbenicillin or ticarcillin
may make these conditions worse, because these medication contain a large amount
of salt
-
Cystic fibrosis Patients with cystic fibrosis may have an increased
risk of fever and skin rash when receiving piperacillin
-
Kidney disease Patients with kidney disease may have an increased
risk of side effects
-
Mononucleosis - “mono” Patients with
mononucleosis may have an increased risk of skin rash when receiving ampicillin,
bacampicillin, or pivampicillin
-
Phenylketonuria Some strengths of the amoxicillin chewable
tablets contain aspartame, which is changed by the body to phenylalanine,
a substance that is harmful to diseaseds with phenylketonuria.
-
Stomach or intestinal disease, history of - especially colitis, including
colitis causing by antibiotics Patients with a history of stomach or
intestinal disease may be more likely to develop colitis while taking penicillins
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