Penicillins and Beta-Lactamase Inhibitors : Before Using

Penicillins and Beta-Lactamase Inhibitors - Systemic

Penicillins and Beta-Lactamase Inhibitors *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For penicillins, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to any of the penicillins, cephalosporins, or beta-lactamase inhibitors. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Diet Tell your family doctor if you are on a low-sodium - low-salt diet. Some of these medication contain enough sodium to cause problems in some people.

Pregnancy care

Penicillins and beta-lactamase inhibitors have not been studied in pregnant women. However, penicillins have not been shown to cause birth defects or other problems in animal studies.

Breast-feeding problem

Penicillins and sulbactam, a beta-lactamase inhibitor, pass into the breast milk. Even though only small amounts may pass into breast milk, allergys, diarrhea, fungus infections and skin rash may occur in nursing babies.

Use for Children

Penicillins and beta-lactamase inhibitors have been using in child and, in effective doses, are not expected to cause various side effects or problems in child than they do in adults.

Some strengths of the chewable tablets and oral suspensions of amoxicillin and clavulanate combination contain aspartame, which is changed by the body to phenylalanine, a substance that is harmful to diseaseds with phenylketonuria.

Elderly care

Penicillins and beta-lactamase inhibitors have been using in the elderly and have not been shown to cause various side effects or problems in elderly people than they do in adults people.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking a penicillin and beta-lactamase inhibitor combination, it is especially important that your health care professional know if you are taking any of the following:

Anticoagulants - blood thinners
Dipyridamole - Persantine
Divalproex - Depakote
Heparin - Panheprin
Inflammation or pain drug - except narcotics
Pentoxifylline - Trental
Plicamycin - Mithracin
Sulfinpyrazone - Anturane
Valproic acid - Depakene Use of these medication with piperacillin and tazobactam combination or with ticarcillin and clavulanate combination may increase the risk of bleeding

Oral contraceptives - birth control pills Use of penicillins and beta-lactamase inhibitors may prevent oral contraceptives from working properly, increasing the risk for pregnancy

Probenecid - Benemid Probenecid causes penicillins, sulbactam, and tazobactam to build up in the blood. This may increase the risk of side effects. However, your family doctor may want to give you probenecid with a penicillin and beta-lactamase inhibitor combination to treat some infections

Other Information for using

The presence of other medical problems may effect the use of penicillin and beta-lactamase inhibitor combinations. Make sure you tell your family doctor if you have any other medical problems, especially:

Allergies or a history of allergies, such as asthma, eczema, hay fever, or hives Patients with a history of allergies may be more likely to have a severe allergy to a penicillin and beta-lactamase inhibitor combination

Bleeding problems, history of Patients with a history of bleeding problems may be more likely to have bleeding when receiving piperacillin and tazobactam combination or ticarcillin and clavulanate combination

Congestive heart failure - CHF
High blood pressure Large doses of ticarcillin and clavulanate combination may make these conditions worse, because this drug contains a large amount of salt

Cystic fibrosis Patients with cystic fibrosis may have an increased risk of fever and skin rash when receiving piperacillin and tazobactam combination

Kidney disease Patients with kidney disease may have an increased risk of side effects

Liver disease - active or a history of Penicillins and beta-lactamase inhibitor combinations may cause this condition to recur or become worse

Mononucleosis - “mono” Patients with mononucleosis may have an increased risk of skin rash when receiving ampicillin and sulbactam combination

Phenylketonuria Some strengths of the amoxicillin and clavulanate combination chewable tablets and oral suspension contain aspartame, which is changed by the body to phenylalanine.

Stomach or intestinal disease, history of - especially colitis, including colitis causing by antibiotics Patients with a history of stomach or intestinal disease may be more likely to develop colitis while taking penicillins and beta-lactamase inhibitors