Paroxetine - Systemic
Brand Names
Paxil
Paroxetine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For paroxetine, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to paroxetine. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy care
Paroxetine has not been well studied in pregnant
women. Paroxetine must only be using during pregnancy if the potential benefit
outweighs the potential risk to the baby. Before taking this drug, make
sure your family doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding problem
Paroxetine passes into the breast milk. However,
the effects of this drug in nursing babies are not known. Caution must
be using if you are breastfeeding.
Use for Children
Paroxetine has not be shown to be safe and effective
in child or adolescents, 18 years of age or younger. Children may be especially
sensitive to the effects of paroxetine for the treat of depression. This
may increase the risk of a child planning to commit suicide or attempting
to commit suicide. Talk to your family doctor about the chance and benefits of taking
this medication.
Elderly care
In studies that have included elderly people, paroxetine
did not cause various side effects or problems in elderly people than it did
in adults people. However, paroxetine may be removed from the body more slowly
in elderly people. An older adult may need a lower dose than a younger adult.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
paroxetine, it is especially important that your health care professional
know if you are taking any of the following:
-
Aspirin
-
Nonsteroidal anti-inflammatory drugs - NSAIDs - celecoxib " Celebrex ",
diclofenac " Voltaren ", diflunisal " Dolobid ", etodolac " Lodine ",
fenoprofen " Nalfon ", flurbiprofen " Ansaid ", ibuprofen " Advil,
Motrin, Nuprin ", indomethacin " Indocin ", ketoprofen " Orudis, Oruvail ",
ketorolac " Toradol ", meclofenamate " Meclomen ", mefenamic acid
" Ponstel ", meloxicam " Mobic ", nabumatone " Relafen ", naproxen
" Aleve, Anaprox, Naprosyn ", oxaprozin " Daypro ", phenylbutazone,
piroxicam " Feldene ", rofecoxib " Vioxx ", sulindac " Clinoril ",
tolmetin " Tolectin ", valdecoxib " Bextra " Taking any of
these medication with paroxetine may cause bleeding problems.
-
Buspirone - BuSpar
-
Bromocriptine - Parlodel
-
Dextromethorphan - cough drug
-
Levodopa - Sinemet
-
Lithium - Eskalith
-
Meperidine - Demerol
-
Nefazodone - Serzone
-
Pentazocine - Talwin
-
Selective serotonin reuptake inhibitors, other - citalopram "
Celexa ", fluoxetine " Prozac ", fluvoxamine " Luvox ", sertraline
"Zoloft "
-
Street drugs - LSD, MDMA " ecstasy ", marijuana
-
Sumatriptan - Imitrex
-
Tramadol - Ultram
-
Trazodone - Desyrel
-
Tryptophan
-
Venlafaxine - Effexor Using these medication with paroxetine
may increase the risk of developing a rare, but very serious, unwanted effect
known as the serotonin syndrome. This syndrome may cause confusion, diarrhea,
fever, poor coordination, restlessness, shivering, sweating, talking or acting
with excitement you can't control, trembling or shaking, or twitching. If
you develop these symptoms, contact your family doctor as soon as possible.
-
Moclobemide - Manerix The risk of developing serious
unwanted effects, including the serotonin syndrome, is increased. Use of moclobemide
with paroxetine is not recommended. Always it is recommended that 3 to 7 days
be allowed between stopping treat with moclobemide and starting treat
with paroxetine and that 2 weeks be allowed between stopping treat with
paroxetine and starting treat with moclobemide
-
Monoamine oxidase - MAO inhibitor activity - isocarboxazid "
Marplan ", phenelzine " Nardil ", procarbazine " Matulane ", selegiline
" Eldepryl ", tranylcypromine " Parnate " Do not take paroxetine while you are taking or within 2 weeks of taking an
MAO inhibitor
, or you may develop confusion, agitation, restlessness,
stomach or intestinal symptoms, sudden high body temperature, extremely high
blood pressure, severe convulsions, or the serotonin syndrome. At least 14
days must be allowed between stopping treat with one drug - paroxetine
or the MAO inhibitor and starting treat with the other
-
St. John's Wort Taking this medication with paroxetine may
increase the risk of side effects.
-
Thioridazine - Mellaril Taking thioridazine with paroxetine
may cause serious heart problems.
-
Tricyclic antidepressants - amitriptyline " Elavil ", amoxapine
" Asendin ", clomipramine " Anafranil ", desipramine " Norpramin ",
doxepin " Sinequan ", imipramine " Tofranil ", nortriptyline "
Aventyl ", protriptyline " Vivactil ", trimipramine " Surmontil " Taking
a tricyclic antidepressant together with paroxetine may increase the risk
of side effects. Your family doctor may need to adjust the dose of either drug
or check blood levels of the tricyclic antidepressant. Always taking paroxetine
with amitriptyline, clomipramine, or imipramine may increase the risk that
the serotonin syndrome will develop
-
Warfarin - Coumadin or other medications that prevent the blood
from clotting Taking these medication with paroxetine may cause bleeding
problems.
Other Information for using
The presence of other medical
problems may effect the use of paroxetine. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Brain disease or damage
-
Mental retardation
-
Epilepsy or seizures - history of The risk of seizures may
be increased.
-
Glaucoma, narrow angle Patients with this condition must
use paroxetine with caution.
-
Heart disease
-
Heart attack, recent Use must be determined by your family doctor.
-
Kidney disease, severe,
-
Liver disease, severe Higher blood levels of paroxetine may
occur, increasing the risk of side effects
-
Mania - history of The condition may be activated
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