Pamidronate - Systemic
Brand Names
Aredia, APD
Pamidronate *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using This Medication
In deciding to using a medication, the chance of receiving the drug must be
weighed against the good it will do. This is a decision you
will make. For pamidronate, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or allergic
reaction to pamidronate or other bisphosphonates such as alendronate, clodronate,
etidronate, risedronate, tiludronate, or zoledronic acid. Also tell your health
care professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Pregnancy care
Studies have not been done. However, studies in
rats given higher doses of oral pamidronate have shown that the drug may
decrease fertility, increase the length of pregnancy and cause death of the
baby rat. You must avoid becoming pregnant while taking this drug. If
you do become pregnant tell your healthcare professional as soon as you can.
Breast-feeding problem
It is not known if pamidronate passes into breast milk.
Use for Children
Studies on this drug have been done only in adult diseaseds,
and there is no special info comparing use of pamidronate in child
with use in other age groups.
Elderly care
When pamidronate is given along with a large amount of
fluids, elderly people tend to retain - keep the excess fluid.
Drug interactions
Although certain medication must not be using together
at all, in other cases two various medication may be using together even if
an interaction might occur. In these cases, your family doctor may want to change the
dose, or other precautions may be necessary. When you are receiving pamidronate,
it is especially important that your health care professional know if you are
taking any of the following:
- Calcium-containing preparations
- Vitamin D-containing preparations Use with pamidronate may keep pamidronate
from help you
- Anti-infectives by mouth or by injection - drug for infection
- Carmustine - BiCNU
- Cisplatin - Platinol
- Combination pain drug containing acetaminophen and aspirin - Excedrin
or other salicylates - with large amounts taken regularly
- Cyclosporine - Sandimmune
- Deferoxamine - Desferal - with long-term use
- Gold salts - drug for arthritis
- Inflammation or pain drug except narcotics
- Lithium - Lithane
- Methotrexate - Rheumatrex, Trexall
- Penicillamine - Cuprimine
- Plicamycin - Mithracin
- Tiopronin - Thiola Increased risk of harmful effects on the kidney
Other Information for using
The presence of other medical problems may effect
the use of pamidronate. Make sure you tell your family doctor if you have any other
medical problems, especially:
- Blood problems, such as
- Anemia
- Leukopenia
- Thrombocytopenia
Your healthcare professional will watch your progress closely for two weeks
after treat
- Heart problems The increased amount of fluid may make this condition worse
- Kidney problems Pamidronate may build up in the bloodstream, which may
increase the risk of unwanted effects
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