If you will be taking this drug for a long time - for example, more than a few weeks, your family doctor must check your progress at regular appointments.
This drug may add to the effects of alcohol and other CNS depressants - medication that slow down the nervous system, possibly causing drowsiness. Some examples of CNS depressants are antihistamines or drug for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping drug; prescription pain drug or narcotics; barbiturates; drug for seizures; other muscle relaxants; or anesthetics, including some dental anesthetics. Do not drink alcoholic beverages and check with your family doctor before taking any of the medication listed above, while you are using this drug .
This drug may cause some people to have blurred vision or to become drowsy, dizzy, lightheaded, faint, or less alert than they are normally. It may also cause muscle weakness in some people Make sure you know how you react to this drug before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and able to see well .
Orphenadrine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the risk of dental disease, including tooth decay, gum disease and fungus infections.