Brand Names

How to Use

You will be given a fact sheet with your prescription for nafarelin that explains how to use the pump spray bottle. If you have any questions about using the pump spray, ask your health care professional.

To use nafarelin spray :

• Before you use each new bottle of nafarelin, the spray pump needs to be started. To do this, point the bottle away from you and pump the bottle firmly about seven times. A spray must come out by the seventh time you pump the spray bottle This only needs to be done once for each new bottle of nafarelin . Be careful not to breathe in this spray. You could inhale extra doses of nafarelin, since the drug is dissolved in the spray.
• Before you take your daily doses of nafarelin, blow your nose gently. Hold your head forward a little. Put the spray tip into one nostril. Aim the tip toward the back and outside of your nostril. You don't needed to put the tip too far into your nose.
• Close your other nostril off by pressing on the outside of your nose with a finger. Then, sniff in the spray as you pump the bottle once.
• Take the spray bottle out of your nose. Tilt your head back for 30 seconds, to let the spray get onto the back of your nose.
• Repeat these steps for each dose of drug.
• Each time you use the spray bottle, wipe off the tip with a clean tissue or cloth. Keep the blue safety clip and plastic cap on the bottle when you are not using it.
• Every 3 or 4 days you must clean the tip of the spray bottle. To do this, hold the bottle sideways. Rinse the tip with warm water, while wiping the tip with your finger or a soft cloth for about 15 seconds. Dry the tip with a soft cloth or tissue. Replace the cap right after use. Be careful not to get water into the bottle, since this could dilute the drug.

It is important to avoid sneezing when spraying and immediately after using the drug. If you sneeze, the drug may not be absorbed as well.

Use this drug only as directed by your family doctor. Do not use more or less of it and do not use it more often than your family doctor ordered. The exact amount of drug you need has been carefully worked out. Using too much may increase the risk of side effects, while using too little may not improve your condition.

Many boys and girls who have central precocious puberty will not feel sick or will not understand the importance of taking the drug regularly. It is very important that the drug is using exactly as directed and that the proper amount is using at the proper time. It works best when there is a constant amount in the blood. To help keep the amount constant, nafarelin must be given on a regular schedule.

Dosage

• For nasal solution dosage form:
  • For treating central precocious puberty:
    • Children 800 micrograms - mcg - two sprays into each nostril two times a day, once in the morning and once in the evening. This provides a total daily dose of eight sprays or 1600 mcg a day. Sometimes a larger dose may be needed. 1800 mcg a day is provided by using three sprays in alternating nostrils three times a day to provide a total of nine sprays a day.
  • For treating endometriosis:
    • Adults 200 mcg - one spray inhaled into one nostril in the morning and one spray inhaled into the other nostril in the evening, for six months. Begin your treat on Day 2, 3, or 4 of your menstrual period.

Missed dose If you miss a dose of this drug, take it as soon as possible. However, if you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage To store this drug:

• Keep out of the reach of children.
• The bottle must be stored standing upright, with the tip up.
• Store away from heat and direct light.
• Keep the drug from freezing. Do not refrigerate.
• Do not keep outdated drug or drug no longer needed. Be sure that any discarded drug is out of the reach of children.