Muromonab-CD3 : Before Using

Muromonab-CD3 - Systemic

Brand Names

Orthoclone OKT3 Muromonab-CD3 *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For muromonab-CD3, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to muromonab-CD3 or to rodents - such as mice or rats. Muromonab-CD3 is grown in a mouse cell culture. Also tell your health care professional if you are allergic to any other substance, such as preservatives.

Pregnancy care

Studies have not been done in either humans or pets. Muromonab-CD3 may cross the placenta, but it is not known whether it causes harmful effects on the fetus. Before receiving this drug, make sure your family doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding problem

It is not known whether muromonab-CD3 passes into breast milk. Muromonab-CD3 has not been reported to cause problems in nursing babies. However, it may be necessary for you to stop breast-feeding during treat. Be sure you have discussed the chance and benefits of the drug with your family doctor.

Use for Children

There is no special info comparing use of muromonab-CD3 in child with use in other age groups. However, children are more likely to get dehydrated from the diarrhea and vomiting that may be causing by this drug.

Elderly care

Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no special info comparing use of muromonab-CD3 in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are receiving muromonab-CD3, it is especially important that your health care professional know if you are taking any of the following:

Azathioprine - Imuran
Chlorambucil - Leukeran
Corticosteroids - cortisone-like drug
Cyclophosphamide - Cytoxan
Cyclosporine - Sandimmune
Cytarabine - Cytosar-U
Mercaptopurine - Purinethol
Tacrolimus - Prograf There may be an increased risk of infection and development of cancer because muromonab-CD3 reduces the body's ability to fight them

Other Information for using

The presence of other medical problems may effect the use of muromonab-CD3. Make sure you tell your family doctor if you have any other medical problems, especially:

Angina - chest pain
Circulation problems
Convulsions - seizures
Heart attack - recent
Heart problems, other,
Kidney problems
Lung problems
Nervous system problems Increased risk of serious unwanted effects from muromonab-CD3

Blood clots - history of chance of blood clots in transplanted organ or blood vessels

Chickenpox - including recent exposure
Herpes zoster - shingles chance of severe disease effecting other parts of the body

Infection Muromonab-CD3 decreases your body's ability to fight infection