Mibefradil : Before Using

Mibefradil - Systemic

Mibefradil *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For mibefradil, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to mibefradil. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

Mibefradil has not been studied in pregnant women. However, studies in pets have shown that large doses of mibefradil can cause heart defects in rat fetuses. Before taking this drug, make sure your family doctor knows if you are pregnant or may become pregnant.

Breast-feeding problem

It is not known if mibefradil passes into breast milk, however, it passes into the milk of lactating rats. Newborn babies have been reported to be sensitive to other calcium channel blocking agents. Be sure you have discussed the chance and benefits of this drug with your family doctor.

Use for Children

Although there is no special info comparing use of mibefradil in child with use in other age groups, it is not expected to cause various side effects or problems in child than it does in adults.

Elderly care

Elderly people may be more sensitive to the heart rate slowing effects of mibefradil.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking mibefradil, it is especially important that your health care professional know if you are taking any of the following:

Astemizole - Hismanal
Cisapride - Propulsid
Terfenadine - Seldane These medication must not be using with mibefradil because unwanted side effects of medication on the heart may be increased

Atorvastatin - Lipitor
Cerivastatin - Baycol
Lovastatin - Mevacor
Simvastatin - Zocor These medication must not be using with mibefradil because unwanted side effects of medication, such as muscle aches or cramps - rhabdomyolysis, may be increased and may lead to development of kidney problems

Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol " Tenormin ", betaxolol " Kerlone ", carteolol " Cartrol ", carvedilol, " Coreg ", labetalol " Normodyne ", metoprolol " Lopressor ", nadolol " Corgard ", oxprenolol " Trasicor ", penbutolol " Levatol ", pindolol " Visken ", propranolol " Inderal ", sotalol " Sotacor ", timolol " Blocadren "
Digitalis glycosides - Lanoxin
Diltiazem - Cardizem
Verapamil - Calan Effects to slow the heart rate may be increased

Cyclosporine - Sandimmune
Desipramine - Norpramin
Imipramine - Tofranil
Tacrolimus - Prograf Effects of these medication may be increased if they are using with mibefradil

Flecainide - Tambocor
Propafenone - Rythmol Unwanted side effects of medication on the heart may be increased

Other Information for using

The presence of other medical problems may effect the use of mibefradil. Make sure you tell your family doctor if you have any other medical problems, especially:

Heart rhythm or heart rate problems Mibefradil can worsen these conditions