Methyldopa and Thiazide Diuretics - Systemic
Methyldopa and Thiazide Diuretics *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For methyldopa and thiazide
diuretics, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to methyldopa, sulfonamides - sulfa drugs, bumetanide, furosemide,
indapamide, acetazolamide, dichlorphenamide, methazolamide, or thiazide diuretics
- water pills. Also tell your health care professional if you are allergic
to any other substances, such as foods, sulfites or other preservatives, or
dyes.
Pregnancy care
Studies have not shown that methyldopa
causes birth defects or other problems. However, when thiazide diuretics are
using during pregnancy, they may cause side effects including jaundice, blood
problems and low potassium in the newborn infant. Thiazide diuretics have
not been shown to cause birth defects.
Breast-feeding problem
This drug passes into breast milk. Thiazide
diuretics may decrease the flow of breast milk. Therefore, you must avoid
use of thiazide diuretics during the first month of breast-feeding.
Use for Children
Although there is no special info comparing
use of this drug in child with use in other age groups, it is not expected
to cause various side effects or problems in child than it does in adults.
Elderly care
Dizziness or light-headedness, drowsiness, or signs
of too much potassium loss may be more likely to occur in the elderly, who
are more sensitive to the effects of methyldopa and thiazide diuretics.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
methyldopa and thiazide diuretics, it is especially important that your health
care professional know if you are taking any of the following:
-
Digitalis glycosides - heart drug Thiazide diuretics may
cause low potassium in the blood, which can lead to symptoms of digitalis
toxicity
-
Lithium - Lithane chance of lithium overdose, even at usual
doses, may be increased
-
Monoamine oxidase - MAO inhibitor activity - isocarboxazid
" Marplan ", phenelzine " Nardil ", procarbazine " Matulane ",
selegiline " Eldepryl ", tranylcypromine " Parnate " Taking
methyldopa while you are taking or within 2 weeks of taking MAO inhibitors
may cause nervousness; headache, severe high blood pressure and hallucinations
have been reported
Other Information for using
The presence of other medical
problems may effect the use of methyldopa and thiazide diuretics. Make sure
you tell your family doctor if you have any other medical problems, especially:
-
Angina - chest pain Methyldopa may worsen the condition
-
Diabetes mellitus - sugar diabetes Thiazide diuretics may change
the amount of diabetes drug needed
-
Gout - history of Thiazide diuretics may increase the amount
of uric acid in the blood, which can lead to gout
-
High cholesterol Thiazide diuretics may raise cholesterol levels
-
Kidney disease Effects of methyldopa and thiazide diuretics
may be increased because of slower removal from the body. If severe, thiazide
diuretics may not work
-
Liver disease Effects of methyldopa may be increased because
of slower removal from the body. If thiazide diuretics cause loss of too much
water from the body, liver disease can become much worse
-
Lupus erythematosus - history of Thiazide diuretics may worsen
the condition
-
Mental depression - history of Methyldopa can cause mental
depression
-
Pancreatitis - inflammation of the pancreas
-
Parkinson's disease Methyldopa may worsen the condition
-
Pheochromocytoma Methyldopa may interfere with tests for the
condition; in addition, there have been reports of increased blood pressure
-
If you have taken methyldopa in the past and developed liver problems
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