Brand Names

How to Use

Take this drug only as directed by your family doctor . Do not take more or less of it and do not take it more often than your family doctor ordered. The exact amount of drug you need has been carefully worked out. Taking too much may increase the risk of side effects, while taking too little may not improve your condition.

Methotrexate may cause nausea. Even if you begin to feel ill, do not stop using this drug without first checking with your family doctor . Ask your health care professional for ways to lessen these effects. If you begin vomiting, check with your family doctor.

If you vomit shortly after taking a dose of methotrexate, check with your family doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

Dosage

The number of tablets that you take or doses of injection that you use depends on the strength of the drug. Always the number of doses you take each day, the time allowed between doses and the length of time you take the drug depend on the medical problem for which you are taking methotrexate .

• For oral dosage form - tablets:
  • For psoriasis :
    • Adults 2.5 to 5 milligrams - mg every twelve hours for three doses once a week, or 10 to 25 mg once a week. Your family doctor may increase the dose as needed.
    • Children Dose must be determined by your family doctor.
  • For rheumatoid arthritis:
    • Adult 2.5 to 5 mg every twelve hours for three doses once a week, or 7.5 mg once a week. Your family doctor may increase the dose as needed.
    • Children Dose must be determined by your family doctor.
• For injection dosage form:
  • For psoriasis:
    • Adults To start, 10 mg injected into a muscle or vein once a week. Your family doctor may increase the dose as needed.
    • Children Dose must be determined by your family doctor.

Missed dose If you miss a dose of this drug, do not take the missed dose at all and do not double the next one. Instead, go back to your regular dosing schedule and check with your family doctor.

Storage To store this drug:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the drug to break down.
• Do not keep outdated drug or drug no longer needed. Be sure that any discarded drug is out of the reach of children.