Isoniazid - Systemic
Brand Names
Laniazid, Nydrazid, Isotamine, PMS Isoniazid, INH
Isoniazid *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For isoniazid, the following
must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to isoniazid, ethionamide - Trecator-SC, pyrazinamide,
or niacin - Nicobid, nicotinic acid. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Diet Make certain your health care professional
knows if you are on a low-sodium, low-sugar, or any other special diet. Most
medication contain more than just the active ingredient and many liquid medication
contain alcohol.
Pregnancy care
Isoniazid has not been shown to cause birth defects
or other problems or pets. Studies in rats and rabbits have shown
that isoniazid may increase the risk of fetal death. However, tuberculosis
is a very serious disease and many women have been treated with isoniazid
during pregnancy with no problems occurring in their babies.
Breast-feeding problem
Isoniazid passes into the breast milk. However,
isoniazid has not been reported to cause problems in nursing babies. Always
there is not enough isoniazid in breast milk to protect or treat babies who
have been exposed to tuberculosis.
Use for Children
Isoniazid can cause serious side effects in any patient.
Therefore, it is especially important that you discuss with the child's family doctor
the good that this drug may do as well as the chance of using it.
Elderly care
Hepatitis may be especially likely to occur in diseaseds
over 50 years of age, who are usually more sensitive than adults people to
the effects of isoniazid.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
or receiving isoniazid it is especially important that your health care professional
know if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Alfentanil - Alfenta
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Androgens - male hormones
-
Antithyroid agents - drug for overactive thyroid
-
Carmustine - BiCNU
-
Chloroquine - Aralen
-
Dantrolene - Dantrium
-
Daunorubicin - Cerubidine
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Estrogens - female hormones
-
Etretinate - Tegison
-
Gold salts - drug for arthritis
-
Hydroxychloroquine - Plaquenil
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Methyldopa - Aldomet
-
Naltrexone - Trexan - with long-term, high-dose use
-
Oral contraceptives - birth control pills containing estrogen
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Plicamycin - Mithracin
-
Valproic acid - Depakene These medication may increase
the risk of liver damage if taken with isoniazid
-
Carbamazepine - Tegretol
-
Phenytoin - Dilantin These medication may increase the
risk of liver damage if taken with isoniazid. There may also be an increased
risk of side effects of carbamazepine and phenytoin
-
Disulfiram - Antabuse This drug may increase the
risk of liver damage and side effects, such as dizziness, lack of coordination,
irritability and trouble in sleeping
-
Ketoconazole - Nizoral
-
Rifampin - Rifadin Use of these medication with isoniazid
can lower the blood levels of ketoconazole or rifampin, decreasing their effects
Other Information for using
The presence of other medical
problems may effect the use of isoniazid. Make sure you tell your family doctor if
you have any other medical problems, especially:
-
Alcohol abuse - or history of
-
Liver disease There may be an increased risk of hepatitis
with daily drinking of alcohol or in diseaseds with liver disease
-
Kidney disease - severe There may be an increased risk of
side effects in diseaseds with severe kidney disease
-
Seizure disorders such as epilepsy There may be an increased
risk of seizures - convulsions in some diseaseds
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