HMG-CoA Reductase Inhibitors : Before Using

HMG-CoA Reductase Inhibitors - Systemic

HMG-CoA Reductase Inhibitors *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For HMG-CoA reductase inhibitors, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to HMG-CoA reductase inhibitors. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Diet Before prescribing medication to lower your cholesterol, your family doctor will probably try to control your condition by prescribing a personal diet for you. Such a diet will be lower in total fat, particularly saturated fat and dietary cholesterol. Many people are able to control their condition by carefully following their family doctor's orders for proper diet and exercise Medicine is prescribed only when additional help is needed and is effective only when a schedule of diet and exercise is properly followed.

Always this drug is less effective if you are greatly overweight. It may be very important for you to go on a reducing diet. However, check with your family doctor before going on any diet.

Pregnancy care

HMG-CoA reductase inhibitors must not be using during pregnancy or by women who plan to become pregnant in the near future. These medication block formation of cholesterol, which is necessary for the fetus to develop properly. HMG-CoA reductase inhibitors may cause birth defects or other problems in the baby if taken during pregnancy. An effective form of birth control must be using during treat with these medication Check with your family doctor immediately if you think you have become pregnant while taking this drug . Be sure you have discussed this with your family doctor.

Breast-feeding problem

These medication are not recommended for use during breast-feeding because they may cause unwanted effects in nursing babies.

Use for Children

Studies on this drug have been done only in adult diseaseds and there is no special info comparing use of HMG-CoA reductase inhibitors in child with use in other age groups. However, atorvastatin, lovastatin and simvastatin have been using in a limited number of children under 18 years of age. Early information seems to show that these medication may be effective in child, but their long-term safety has not been studied.

Elderly care

This drug has been tested in a limited number of diseaseds 65 years of age or older and has not been shown to cause various side effects or problems in elderly people than it does in adults people.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking HMG-CoA reductase inhibitors, it is especially important that your health care professional know if you are taking any of the following:

Cyclosporine - Sandimmune
Gemfibrozil - Lopid
Clofibrate - Atromid-S
Fenofibrate - Tricor
Niacin Use of these medication with an HMG-CoA reductase inhibitor may increase the risk of developing muscle problems and kidney failure

Digoxin - Lanoxin Use with atorvastatin, fluvastatin, or simvastatin may increase blood levels of digoxin, increasing the risk of side effects

Oral contraceptives, - birth control tablets Atorvastatin may increase the blood levels of the birth control hormones, increasing the risk of side effects

HIV protease inhibitors - Amprenavir " Agenerase ", Indinavir " Crixivan ", Nelfinavir " Viracept ", Ritonavir " Norvir ", Saquinavir " Fortovase, Invirase "
Nefazodone - e.g. Serzone Use with simvastatin may increase the risk of developing muscle problems and kidney failure

Verapamil - e.g. Calan, Isoptin Use with simvastatin may increase the risk of muscle problems

Other Information for using

The presence of other medical problems may effect the use of HMG-CoA reductase inhibitors. Make sure you tell your family doctor if you have any other medical problems, especially:

Alcohol abuse - or history of
Liver disease Use of this drug may make liver problems worse

Convulsions - seizures, not well-controlled,
Organ transplant with therapy to prevent transplant rejection
If you have recently had major surgery Patients with these conditions may be at risk of developing problems that may lead to kidney failure