Glyburide and Metformin - Systemic
Brand Names
Glucovance
Glyburide and Metformin *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For glyburide and metformin,
the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual
or allergy to glyburide or metformin. Always tell your health care
professional if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy care
Glyburide and metformin combination has not been
studied in pregnant women or pets. However, independent studies with glyburide
and also with metformin have not shown that either drug causes birth defects
or other problems in animal studies. It is easier during pregnancy to control
your blood sugar by using injections of insulin rather than by taking oral
diabetes medication. Close control of your blood sugar can reduce the risk
of your baby gaining too much weight, having birth defects, or having high
blood sugar before birth. Before taking this drug, make sure your family doctor
knows if you are pregnant or if you may become pregnant.
Breast-feeding problem
It is not known whether glyburide or metformin
passes into human breast milk. Although most medication pass into breast milk
in small amounts, many of them may be using safely while breast-feeding. Mothers
who are taking this drug and who wish to breast-feed must discuss this
with their family doctor.
Use for Children
Studies on this drug have been done only in
adult diseaseds and there is no special info comparing use of glyburide
and metformin in child with use in other age groups.
Elderly care
This drug has been tested and has not been
shown to cause various side effects or problems in elderly people than it
does in adults people.
Drug interactions
Although certain medication must not be using together at all, in other cases
two various medication may be using together even if an interaction might
occur. In these cases, your family doctor may want to change the dose, or other precautions
may be necessary. When you are taking glyburide and metformin, it is especially
important that your health care professional know if you are taking any of
the following:
-
Alcohol Drinking alcohol may increase the risk of developing
lactic acidosis andvery low blood sugar.
-
Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol
" Tenormin ", betaxolol " Kerlone ", bisoprolol " Zebeta ", carteolol
" Cartrol ", labetalol " Normodyne ", metoprolol " Lopressor ",
nadolol " Corgard ", oxprenolol " Trasicor ", penbutolol " Levatol ",
pindolol " Visken ", propranolol " Inderal ", sotalol " Betapace ",
timolol " Blocadren " Beta-adrenergic blocking agents can hide
the symptoms of low blood sugar. Because of this, a person with diabetes might
not recognize that he or she has low blood sugar and might not take immediate
steps to treat it.
-
Cimetidine - Tagamet
-
Furosemide - Lasix Use with a drug that contains
metformin may cause high blood levels of metformin, which may increase the
risk of low blood sugar or other side effects.
Other Information for using
The presence of other medical problems may effect the use of glyburide
and metformin. Make sure you tell your family doctor if you have any other medical
problems, especially:
-
Acid in the blood - acidosis or ketoacidosis
-
Surgery - major Use of insulin is best to help control diabetes
in diseaseds with these conditions.
-
Blood poisoning
-
Dehydration - severe
-
Heart or blood vessel disorders
-
Kidney disease
-
Liver disease Lactic acidosis can occur in these conditions
and chance of it occurring are even greater with a drug that contains
metformin.
-
Kidney, heart, or other problems that require medical tests or examinations
that use certain medication called contrast agents, with x-ray exams Because
this drug contains metformin, your family doctor must advise you to stop taking
it before you have any medical exams or diagnostic tests that might cause
less urine output than usual; you may be advised to start taking the drug
again 48 hours after the exams or tests if your kidney function is tested
and found to be normal.
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