Fore Safe Use

The best for you that your family doctor check your progress at regular appointments to make sure this drug does not cause unwanted effects . Plan on going to see your family doctor every year, but some family doctors require appointments more often.

It is not yet known whether the use of vaginal estrogens increases the risk of breast cancer in women. Therefore, it is very important that you regularly check your breasts for any unusual lumps or discharge. Report any problems to your family doctor. You must also have a mammogram - x-ray pictures of the breasts done if your family doctor recommends it.

If you think that you may be pregnant, stop using the drug immediately and check with your family doctor .

Tell the family doctor in charge that you are using this drug before having any laboratory test, because some test results may be effected.

For vaginal creams

• Avoid using latex condoms, diaphragms, or cervical caps for up to 72 hours after using estrogen vaginal creams. Certain estrogen products may contain oils in the creams that can weaken latex - rubber products and cause condoms to break or leak, or cervical caps or diaphragms to wear out sooner. Check with your health care professional to make sure the vaginal estrogen product you are using can be using with latex devices.
• This drug is often using at bedtime to increase effectiveness through better absorption.
• Vaginal creams or suppositories will melt and leak out of the vagina. A minipad or sanitary napkin will protect your clothing Do not use tampons - like those using for menstrual periods since they may soak up the drug and make the drug less effective.
• Avoid exposing your male sexual partner to your vaginal estrogen cream or suppository by not having sexual intercourse right after using these medication. Your male partner might absorb the drug through his penis if it comes in contact with the drug.

For estradiol vaginal insert

• It is not necessary to remove the vaginal insert for sexual intercourse unless desired.
• If you do take it out or if it accidentally slips or comes out of the vagina, you can replace the vaginal insert in the vagina after washing it with lukewarm water Never use hot or boiling water .
• If it slips down, gently push it upwards back into place.
• Replace the vaginal insert every 3 months.