Estramustine - Systemic
Brand Names
Emcyt, Estracyt
Estramustine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For estramustine, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to estramustine, estrogens, or mechlorethamine.
Pregnancy care
There is a risk that this drug may cause birth
defects if the male is taking it at the time of conception. It may also cause
permanent sterility after it has been taken for a while. Be sure that you
have discussed this with your family doctor before taking this drug. Before taking
estramustine, make sure your family doctor knows if you intend to have children.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of estramustine in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
estramustine, it is especially important that your health care professional
know if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Androgens - male hormones
-
Anti-infectives by mouth or by injection - drug for infection
-
Antithyroid agents - drug for overactive thyroid
-
Carbamazepine - Tegretol
-
Carmustine - BiCNU
-
Chloroquine - Aralen
-
Dantrolene - Dantrium
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Estrogens - female hormones
-
Etretinate - Tegison
-
Gold salts - drug for arthritis
-
Hydroxychloroquine - Plaquenil
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Methyldopa - Aldomet
-
Naltrexone - Trexan - with long-term, high-dose use
-
Oral contraceptives - birth control pills containing estrogen
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Phenytoin - Dilantin
-
Plicamycin - Mithracin
-
Valproic acid - Depakene May increase the risk of liver
problems
-
Tobacco, smoking Smoking causes narrowing of blood vessels
and may increase the risk of serious circulation problems, which can lead
to stroke or heart attack
Other Information for using
The presence of other medical
problems may effect the use of estramustine. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Asthma
-
Epilepsy
-
Mental depression - or history of
-
Migraine headaches
-
Kidney disease Fluid retention sometimes causing by estramustine
may worsen these conditions
-
Blood clots - or history of
-
Stroke - or history of
-
Recent heart attack or stroke May be worsened because of blood
vessel problems causing by estramustine
-
Chickenpox - including recent exposure
-
Herpes zoster - shingles chance of severe disease effecting other
parts of the body
-
Diabetes mellitus - sugar diabetes Estramustine may change
the amount of antidiabetic drug needed
-
Gallbladder disease - or history of May be worsened by estramustine
-
Heart or blood vessel disease Estramustine can cause circulation
problems
-
Jaundice or hepatitis - or history of or other liver disease Effects,
including liver problems, may be increased
-
Stomach ulcer May be aggravated by estramustine
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