Eflornithine - Systemic
Brand Names
Ornidyl
Eflornithine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using This Medication
In deciding to using a medication, the chance of taking the drug must be
weighed against the good it will do. This is a decision you
will make. For eflornithine, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to eflornithine. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy care
Studies have not been done. However, studies
in pets have shown that eflornithine causes death of the fetus and birth
defects. Before taking this drug, make sure your family doctor knows if you are
pregnant or if you may become pregnant.
Breast-feeding problem
It is not known whether eflornithine passes into
breast milk. Although most medication pass into breast milk in small amounts,
many of them may be using safely while breast-feeding. Mothers who are receiving
this drug and who wish to breast-feed must discuss this with their family doctor.
Use for Children
Studies on this drug have been done only in adult
diseaseds and there is no special info comparing use of eflornithine
in child with use in other age groups.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of eflornithine in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are receiving
eflornithine, it is especially important that your health care professional
know if you are taking any of the following:
-
Amphotericin B by injection - Fungizone
-
Antineoplastics - cancer drug
-
Antithyroid agents - drug for overactive thyroid
-
Azathioprine - Imuran
-
Chloramphenicol - Chloromycetin
-
Colchicine
-
Cyclophosphamide - Cytoxan
-
Flucytosine - Ancobon
-
Ganciclovir - Cytovene
-
Interferon - Intron A, Roferon-A
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Plicamycin - Mithracin
-
Zidovudine - AZT, Retrovir Caution must be using if
these medication and eflornithine are using together; receiving eflornithine
while you are using these medication may make anemia and other blood problems
worse
-
Anti-infectives by mouth or by injection - drug for infection
-
Chloroquine - Aralen
-
Cisplatin - Platinol
-
Deferoxamine - Desferal - with long-term use
-
Hydroxychloroquine - Plaquenil
-
Inflammation or pain drug, except narcotics,
-
Quinine - Quinamm Use of any of these medication with
eflornithine may increase the risk of hearing loss
Other Information for using
The presence of other medical
problems may effect the use of eflornithine. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Anemia or other blood problems Eflornithine may cause blood
problems, making the problems you already have worse
-
Hearing loss Long-term treat with eflornithine may increase
your risk of hearing loss
-
Kidney disease Patients with kidney disease may have an increased
risk of side effects
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