Diclofenac and Misoprostol : Before Using - Arthrotec 50, Arthrotec 75

Diclofenac and Misoprostol - Systemic

Brand Names

Arthrotec 50, Arthrotec 75 Diclofenac and Misoprostol *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For diclofenac and misoprostol combination, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to diclofenac or other nonsteroidal anti-inflammatory drugs - NSAIDs, to misoprostol, or to any of the following medication:

Aspirin or other salicylates
Prostaglandin analogs

Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

Diclofenac and misoprostol combination must not be using during pregnancy.

Before starting to take diclofenac and misoprostol combination, you must have had a negative pregnancy test within the previous 2 weeks. Always you must start taking this combination only on the second or third day of your next normal menstrual period. In addition, it will be necessary that you use an effective form of birth control while taking this drug. Be sure that you have discussed this with your family doctor before taking diclofenac and misoprostol combination.

Studies on birth defects with the diclofenac and misoprostol combination have not been done. However, there is a risk that diclofenac may cause unwanted effects on the heart or blood flow of the fetus or newborn baby if taken regularly during the last few months of pregnancy. Always studies in pets have shown that diclofenac, if taken late in pregnancy, may increase the length of pregnancy, prolong labor, or cause other problems during delivery. Diclofenac causing unwanted effects on the formation of bones in pets.

Misoprostol has been shown to cause contractions and bleeding of the uterus. It may also cause miscarriage.

Breast-feeding problem

It is not known whether diclofenac and misoprostol combination passes into breast milk. Diclofenac passes into breast milk. Diclofenac and misoprostol combination is not recommended for use during breast-feeding.

Use for Children

Studies on this drug have been done only in adult diseaseds and there is no special info comparing use of diclofenac and misoprostol combination in child with use in other age groups.

Elderly care

Certain side effects, such as confusion, swelling of the face, feet, or lower legs, or sudden decrease in the amount of urine, may be especially likely to occur in elderly diseaseds, who are usually more sensitive than adults people to the effects of nonsteroidal anti-inflammatory drugs. Always elderly people are more likely than adults people to get sick if this drug causes stomach problems.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking diclofenac and misoprostol combination, it is especially important that your health care professional know if you are taking any of the following:

Anticoagulants - blood thinners
Corticosteroids - prednisone or other cortisone-like medication The risk of bleeding may be increased

Aspirin The risk of serious side effects may be increased if aspirin is using together with diclofenac and misoprostol combination on a regular basis

Cyclosporine - Sandimmune
Digitalis glycosides - heart drug
Lithium - Lithane
Methotrexate - Mexate Higher blood levels of these medication and an increased risk of side effects may occur

Amiloride - Midamor
Spironolactone - Aldactone
Triamterene - Dyrenium May cause high blood levels of potassium, which may increase the risk of side effects

Other Information for using

The presence of other medical problems may effect the use of diclofenac and misoprostol combination. Make sure you tell your family doctor if you have any other medical problems, especially:

Alcohol abuse
Bleeding problems
Hepatitis or other liver disease
Kidney disease - or history of
Tobacco use - or recent history of
Stomach ulcer, or other stomach or intestinal problems
Systemic lupus erythematosus The risk of side effects may be increased

Anemia
Asthma
Dehydration or
Fluid retention - swelling of feet or lower legs
Heart disease
High blood pressure
Low platelet count
Low white blood cell count
Porphyria - liver
Volume depletion Diclofenac and misoprostol combination may make these conditions worse