Cyclophosphamide - Systemic
Brand Names
Cytoxan, Neosar, Procytox
Cyclophosphamide *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For cyclophosphamide,
the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to cyclophosphamide.
Pregnancy care
This drug may cause few various birth defects
if either the male or female is taking it at the time of conception or if
it is taken during pregnancy. In addition, many cancer medication may cause
sterility. Although sterility occurs commonly with cyclophosphamide, it is
usually only temporary.Be sure that you have discussed this with your family doctor before taking this
drug. It is best to use some kind of birth control while you are taking
cyclophosphamide. Tell your family doctor right away if you think you have become
pregnant while taking cyclophosphamide.
Breast-feeding problem
Cyclophosphamide passes into the breast milk. Because
this drug may cause serious side effects, breast-feeding is generally
not recommended while you are taking it.
Use for Children
This drug has been tested in child and has
not been shown to cause various side effects or problems than it does in
adults.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. Although there is no special info
comparing use of cyclophosphamide in the elderly with use in other age groups,
it is not expected to cause various side effects or problems in elderly people
than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
or receiving cyclophosphamide, it is especially important that your health
care professional know if you are taking any of the following:
-
Amphotericin B by injection - Fungizone
-
Antithyroid agents - drug for overactive thyroid
-
Chloramphenicol - Chloromycetin
-
Colchicine
-
Flucytosine - Ancobon
-
Ganciclovir - Cytovene
-
Interferon - Intron A, Roferon-A
-
Methotrexate
-
Plicamycin - Mithracin
-
Zidovudine - AZT, Retrovir
-
If you have ever been treated with radiation or cancer medication Cyclophosphamide
may increase the side effects of medication or radiation therapy on the blood
-
Cocaine Cyclophosphamide may increase the effects and toxicity
of this drug
-
Cytarabine Cyclophosphamide may increase the effects of this
drug on the heart and blood
-
Azathioprine - Imuran
-
Chlorambucil - Leukeran
-
Corticosteroids - cortisone-like drug
-
Cyclosporine - Sandimmune
-
Mercaptopurine - Purinethol
-
Muromonab-CD3 - monoclonal antibody - Orthoclone OKT3 There
may be an increased risk of infection and development of cancer because cyclophosphamide
reduces the body's ability to fight them
-
Probenecid - Benemid
-
Sulfinpyrazone - Anturane Cyclophosphamide may increase
the amount of uric acid in the blood. Since these medication are using to lower
uric acid levels, they may not work as well in diseaseds taking cyclophosphamide
Other Information for using
The presence of other medical
problems may effect the use of cyclophosphamide. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Chickenpox - including recent exposure
-
Herpes zoster - shingles chance of severe disease effecting other
parts of the body
-
Gout - history of
-
Kidney stones - history of Cyclophosphamide may increase levels
of uric acid in the body, which can cause gout or kidney stones
-
Infection Cyclophosphamide can decrease your body's ability
to fight infection
-
Kidney disease Effects of cyclophosphamide may be increased
because of slower removal from the body
-
Liver disease The effect of cyclophosphamide may be decreased
-
Prior removal of adrenal gland - s Toxic effects of cyclophosphamide
may be increased, dosage adjustment may be necessary
-
Tumor cell accumulation Increased risk of tumor cells entering
the bone marrow, due to bone marrow depression from high doses of cyclophosphamide
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