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Cough/Cold Combinations - Systemic

Description and Brand Names *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Category

Description Drug

Cough/cold combinations are using mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be using for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm - pronounced flem with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant and an analgesic, in addition to a drug for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Always in general, it is best to buy a product that includes only those medication you really need. If you have questions about which product to buy, check with your pharmacist.

Since various products contain ingredients that will have various precautions and side effects, it is important that you know the ingredients of the drug you are taking. The various kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines Antihistamines are using to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are: bromodiphenhydramine - broe-moe-dye-fen-HYE-dra-meen, brompheniramine - brome-fen-EER-a-meen, carbinoxamine - kar-bi-NOX-a-meen, chlorpheniramine - klor-fen-EER-a-meen, dexchlorpheniramine - dex-klor-fen-EER-a-meen, diphenhydramine - dye-fen-HYE-dra-meen, doxylamine - dox-ILL-a-meen, phenindamine - fen-IN-da-meen, pheniramine - fen-EER-a-meen, phenyltoloxamine - fen-ill-tole-OX-a-meen, pyrilamine - peer-ILL-a-meen, promethazine - proe-METH-a-zeen and triprolidine - trye-PROE-li-deen.

Decongestants Decongestants, such as ephedrine - e-FED-rin, phenylephrine - fen-ill-EF-rin and pseudoephedrine - soo-doe-e-FED-rin, produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in diseaseds who have high blood pressure.

Antitussives To help relieve coughing these combinations contain either a narcotic "codeine - KOE-deen, dihydrocodeine - dye-hye-droe-KOE-deen, hydrocodone - hye-droe-KOE-done or hydromorphone - hye-droe-MOR-fone " or a nonnarcotic "carbetapentane - kar-bay-ta-PEN-tane, caramiphen - kar-AM-i-fen, or dextromethorphan - dex-troe-meth-OR-fan " antitussive. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if using for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the drug.

Expectorants Guaifenesin - gwye-FEN-e-sin works by loosening the mucus or phlegm in the lungs. Other ingredients added as expectorants - for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide and sodium citrate have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics Analgesics, such as acetaminophen - a-seat-a-MIN-oh-fen, aspirin and other salicylates "such as salicylamide - sal-i-SILL-a-mide and sodium salicylate - SOE-dee-um sa-LI-sill-ate " are using in these combination medication to help relieve the aches and pain that may occur with the common cold.

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medication are taken together for a long time. However, taking the recommended amounts of combination medication that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics Anticholinergics such as homatropine - hoe-MA-troe-peen may help produce a drying effect in the nose and chest.

Some of these combinations are available only with your family doctor's prescription. Others are available without a prescription; however, your health care professional may have special instructions on the proper dose of the drug for your medical condition.

Cough/cold combinations are available in the following dosage forms:

Brand Names

Some commonly using brand names are:

In the USA

In Canada

Note:

For quick reference the following cough/cold combinations are numbered to match the preceding corresponding brand names.

Note:

Products containing phenylpropanolamine were removed from the USAand Canadian Markets in November 2000.

Antihistamine and antitussive combinations 1. Chlorpheniramine and Codeine - klor-fen-EER-a-meenand KOE-deen* 2. Chlorpheniramine and Dextromethorphan - klor-fen-EER-a-meen and dex-troe-meth-OR-fan† 3. Chlorpheniramine and Hydrocodone - klor-fen-EER-a-meen and hye-droe-KOE-done† 4. Phenyltoloxamine and Hydrocodone - fen-ill-tole-OX-a-meen and hye-droe-KOE-done* 5. Promethazine and Codeine - proe-METH-a-zeen and KOE-deen† 6. Promethazineand Dextromethorphan - proe-METH-a-zeenand dex-troe-meth-OR-fan† 7. Pyrilamineand Codeine - peer-ILL-a-meen and KOE-deen† * Not commercially available in the USA † Not commercially available in Canada Generic name product may be available in the USA Antihistamine, antitussive and analgesic combinations 8. Doxylamine, Codeine and Acetaminophen - dox-ILL-a-meen, KOE-deen and a-seat-a-MIN-oh-fen* * Not commercially available in the USA Antihistamine, antitussive and expectorant combinations 9. Diphenhydramine, Codeine and Ammonium Chloride - dye-fen-HYE-dra-meen, KOE-deen and a-MOE-nee-um KLOR-ide* 10. Diphenhydramine, Dextromethorphan and Ammonium Chloride - dye-fen-HYE-dra-meen, dex-troe-meth-OR-fan and a-MOE-nee-um KLOR-ide* 11. Pheniramine, Codeine and Guaifenesin - fen-EER-a-meen, KOE-deen and gwye-FEN-e-sin* 12. Pheniramine, Pyrilamine, Hydrocodone, Potassium Citrate and Ascorbic Acid - fen-EER-a-meen, peer-ILL-a-meen,hye-droe-KOE-done, poe-TAS-ee-um SI-trate and a-SKOR-bik AS-id† 13. Promethazine, Codeine and Potassium Guaiacolsulfonate - proe-METH-a-zeen, KOE-deen and poe-TAS-ee-um gwye-a-kol-SUL-fon-ate* * Not commercially available in the USA † Not commercially available in Canada Antihistamine and decongestant combinations 14. Promethazine and Phenylephrine - proe-METH-a-zeen,and fen-ill-EF-rin † 15. Pheniramine, Pyrilamine and Phenyltoloxamine - fen-EER-a-meen, peer-ILL-a-meen and fen-ill-tole-OX-a-meen† † Not commercially available in Canada Antihistamine, decongestant and antitussive combinations 16. Brompheniramine, Phenylephrine and Codeine - brome-fen-EER-a-meen, fen-ill-EF-rin and KOE-deen 17. Brompheniramine, Pseudoephedrine and Dextromethorphan - brome-fen-EER-a-meen, soo-doe-e-FED-rin and dex-troe-meth-OR-fan† 18. Carbinoxamine, Pseudoephedrine and Dextromethorphan - kar-bi-NOX-a-meen, soo-doe-e-FED-rin and dex-troe-meth-OR-fan† 19. Chlorpheniramine, Pyrilamine, Phenylephrine, Pseudoephedrine and Hydrocodone - klor-fen-EER-a-meen, peer-ILL-a-meen,fen-ill-EF-rin, soo-doe-e-FED-rin and hye-droe-KOE-done † 20. Chlorpheniramine, Ephedrine, Phenylephrine and Carbetapentane - klor-fen-EER-a-meen, e-FED-rin, fen-ill-EF-rin and kar-bay-ta-PEN-tane† 21. Chlorpheniramine, Phenylephrine and Dextromethorphan - klor-fen-EER-a-meen, fen-ill-EF-rin and dex-troe-meth-OR-fan† 22. Chlorpheniramine, Phenylephrine and Hydrocodone - klor-fen-EER-a-meen, fen-ill-EF-rin and hye-droe-KOE-done† 23. Chlorpheniramine, Pseudoephedrine and Codeine - klor-fen-EER-a-meen, soo-doe-e-FED-rin and KOE-deen† 24. Chlorpheniramine, Pseudoephedrine and Dextromethorphan - klor-fen-EER-a-meen, soo-doe-e-FED-rin and dex-troe-meth-OR-fan 25. Chlorpheniramine, Pseudoephedrine and Hydrocodone - klor-fen-EER-a-meen, soo-doe-e-FED-rin and hye-droe-KOE-done† 26. Chlorpheniramine, Pseudoephedrine and Hydrocodone or Pseudoephedrine andHydrocodone - klor-fen-EER-a-meen,soo-doe-e-FED-rin and hye-droe-KOE-done or soo-doe-e-FED-rin and hye-droe-KOE-done† 27. Doxylamine, Etafedrine and Hydrocodone - dox-ILL-a-meen, et-a-FED-rin and hye-droe-KOE-done* 28. Pheniramine, Phenylephrine and Dextromethorphan - fen-EER-a-meen, fen-ill-EF-rin and dex-troe-meth-OR-fan* 29. Promethazine, Phenylephrine and Codeine - proe-METH-a-zeen, fen-ill-EF-rin and KOE-deen† 30. Triprolidine, Pseudoephedrine and Codeine - trye-PROE-li-deen, soo-doe-e-FED-rin and KOE-deen * Not commercially available in the USA † Not commercially available in Canada Antihistamine, decongestant, antitussive and analgesiccombinations 31. Chlorpheniramine, Pheniramine, Pyrilamine, Phenylephrine, Hydrocodone, Salicylamide,Caffeine and Ascorbic Acid - klor-fen-EER-a-meen,fen-EER-a-meen, peer-ILL-a-meen, fen-ill-EF-rin, hye-droe-KOE-done, sal-i-SILL-a-mide,kaf-EEN and a-SKOR-bik AS-id† 32. Chlorpheniramine,Phenylephrine, Hydrocodone, Acetaminophen and Caffeine - klor-fen-EER-a-meen, fen-ill-EF-rin, hye-droe-KOE-done, a-seat-a-MIN-oh-fen,and kaf-EEN† 33. Chlorpheniramine, Pseudoephedrine, Codeine and Acetaminophen - klor-fen-EER-a-meen, soo-doe-e-FED-rin,KOE-deen and a-seat-a-MIN-oh-fen* 34. Chlorpheniramine,Pseudoephedrine, Dextromethorphan and Acetaminophen - klor-fen-EER-a-meen, soo-doe-e-FED-rin, dex-troe-meth-OR-fan and a-seat-a-MIN-oh-fen 35. Doxylamine, Pseudoephedrine, Dextromethorphan andAcetaminophen - dox-ILL-a-meen, soo-doe-e-FED-rin,dex-troe-meth-OR-fan and a-seat-a-MIN-oh-fen 36. Pyrilamine, Pseudoephedrine, Dextromethorphan and Acetaminophen - peer-ILL-a-meen, soo-doe-e-FED-rin, dex-troe-meth-OR-fan and a-seat-a-MIN-oh-fen† * Not commercially available in the USA † Not commercially available in Canada Antihistamine, decongestant, antitussive and expectorantcombinations 37. Brompheniramine, Phenylephrine, Codeine and Guaifenesin - brome-fen-EER-a-meen, fen-ill-EF-rin, KOE-deen and gwye-FEN-e-sin* 38. Brompheniramine, Phenylephrine, Hydrocodone and Guaifenesin - brome-fen-EER-a-meen, fen-ill-EF-rin, hye-droe-KOE-done and gwye-FEN-e-sin* 39. Chlorpheniramine, Ephedrine, Phenylephrine, Dextromethorphan,Ammonium Chloride and Ipecac - klor-fen-EER-a-meen,e-FED-rin, fen-ill-EF-rin, dex-troe-meth-OR-fan, a-MOE-nee-um KLOR-ide andIP-e-kak† 40. Chlorpheniramine, Phenylephrine, Codeine and AmmoniumChloride - klor-fen-EER-a-meen, fen-ill-EF-rin,KOE-deen and a-MOE-nee-um KLOR-ide† 41. Chlorpheniramine,Phenylephrine, Codeine and Potassium Iodide - klor-fen-EER-a-meen, fen-ill-EF-rin, KOE-deen and por-TAS-ee-um EYE-oh-dyed† 42. Chlorpheniramine, Phenylephrine, Dextromethorphan,and Guaifenesin - klor-fen-EER-a-meen,fen-ill-EF-rin, dex-troe-meth-OR-fan and gwye-FEN-e-sin† 43. Chlorpheniramine, Phenylephrine, Dextromethorphan, Guaifenesin and AmmoniumChloride - klor-fen-EER-a-meen, fen-ill-EF-rin,dex-troe-meth-OR-fan, gwye-FEN-e-sin and a-MOE-nee-um KLOR-ide† 44. Chlorpheniramine, Pseudoephedrine, Dextromethorphan and Guaifenesin - klor-fen-EER-a-meen, soo-doe-e-FED-rin, dex-troe-meth-OR-fan and gwye-FEN-e-sin* 45. Pyrilamine, Phenylephrine, Hydrocodone and AmmoniumChloride - peer-ILL-a-meen, fen-ill-EF-rin,hye-droe-KOE-done and a-MOE-nee-um KLOR-ide* 46. Triprolidine, Pseudoephedrine, Codeine and Guaifenesin - trye-PROE-li-deen, soo-doe-e-FED-rin, KOE-deen and gwye-FEN-e-sin* * Not commercially available in the USA † Not commercially available in Canada Antihistamine, decongestant, antitussive, expectorant,and analgesic combinations 47. Pheniramine, Phenylephrine, Codeine, Sodium Citrate, Sodium Salicylate andCaffeine - fen-EER-a-meen, fen-ill-EF-rin,KOE-deen, SOE-dee-um SI-trate, SOE-dee-um sa-LI-sill-ate and kaf-EEN† † Not commercially available in Canada Antihistamine, decongestant and expectorant combinations 48. Chlorpheniramine, Ephedrine and Guaifenesin - klor-fen-EER-a-meen, e-FED-rin and gwye-FEN-e-sin† 49. Promethazine, Phenylephrine and Potassium Guaiacolsulfonate - pro-METH-a-zeen, fen-ill-EF-rin and poe-TAS-see-um gwye-a-kol-SUL-fon-ate* * Not commercially available in the USA † Not commercially available in Canada Antitussive and analgesic combination 50. Dextromethorphan and Acetaminophen - dex-troe-meth-OR-fan and a-seat-a-MIN-oh-fen Antitussive and anticholinergic combination 51. Hydrocodone and Homatropine - hye-droe-KOE-done and hoe-MA-troe-peen Generic name product may be available in the USA Antitussive and expectorant combinations 52. Codeine, Ammonium Chloride and Guaifenesin - KOE-deen, a-MOE-nee-um KLOR-ide and gwye-FEN-e-sin* 53. Codeine and Guaifenesin - KOE-deen and gwye-FEN-e-sin† 54. Dextromethorphanand Guaifenesin - dex-troe-meth-OR-fanand gwye-FEN-e-sin 55. Dextromethorphan and Iodinated Glycerol - dex-troe-meth-OR-fan and EYE-oh-di-nay-ted GLI-ser-ole† 56. Hydrocodone and Guaifenesin - hye-droe-KOE-done and gwye-FEN-e-sin† 57. Hydrocodoneand Potassium Guaiacolsulfonate - hye-droe-KOE-done and poe-TAS-see-um gwye-a-kol-SUL-fon-ate† * Not commercially available in the USA † Not commercially available in Canada Generic name product may be available in the USA Decongestant and antitussive combinations 58. Phenylephrine and Hydrocodone - fen-ill-EF-rinand hye-droe-KOE-done 59. Pseudoephedrine and Dextromethorphan - soo-doe-e-FED-rin and dex-troe-meth-OR-fan Decongestant, antitussive and analgesic combinations 60. Pseudoephedrine, Dextromethorphan and Acetaminophen - soo-doe-e-FED-rin, dex-troe-meth-OR-fan and a-seat-a-MIN-oh-fen Decongestant, antitussive and expectorant combinations 61. Phenylephrine, Codeine and Guaifenesin - fen-ill-EF-rin, KOE-deen and gwye-FEN-e-sin† 62. Phenylephrine, Hydrocodone and Guaifenesin - fen-ill-EF-rin, hye-droe-KOE-done and gwye-FEN-e-sin 63. Pseudoephedrine, Codeine and Guaifenesin - soo-doe-e-FED-rin, KOE-deen and gwye-FEN-e-sin 64. Pseudoephedrine, Dextromethorphan and Guaifenesin - soo-doe-e-FED-rin, dex-troe-meth-OR-fan and gwye-FEN-e-sin 65. Pseudoephedrine, Hydrocodone and Guaifenesin - soo-doe-e-FED-rin, hye-droe-KOE-done and gwye-FEN-e-sin† 66. Pseudoephedrine, Hydrocodone and Potassium Guaiacolsulfonate - soo-doe-e-FED-rin, hye-droe-KOE-done and poe-TAS-ee-um gwye-a-kol-SUL-fon-ate† † Not commercially available in Canada Generic name product may be available in the USA Decongestant, antitussive, expectorant and analgesiccombinations 67. Pseudoephedrine, Dextromethorphan, Guaifenesin and Acetaminophen - soo-doe-e-FED-rin, dex-troe-meth-OR-fan, gwye-FEN-e-sin and a-seat-a-MIN-oh-fen Decongestant and expectorant combinations 68. Ephedrine and Guaifenesin - e-FED-rinand gwye-FEN-e-sin† 69. Phenylephrine and Guaifenesin - fen-ill-EF-rin and gwye-FEN-e-sin† 70. Pseudoephedrine and Guaifenesin - soo-doe-e-FED-rin and gwye-FEN-e-sin † Not commercially available in Canada Generic name product may be available in the USA








  

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