Colchicine - Systemic
Colchicine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For colchicine, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to colchicine. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy care
Studies taking large amounts of colchicine
to relieve attacks have not been done. Fertility problems have occurred in
some men taking small amounts of colchicine regularly - preventive treat,
but these problems went away after treat was stopped. Many other men taking
preventive amounts of colchicine have fathered children without stopping treat.
Always many women receiving preventive treat with colchicine have become
pregnant and given birth to normal, healthy babies. Some women receive preventive
amounts of colchicine regularly for a medical condition that can cause fertility
problems or miscarriages. Treatment with colchicine does not increase and
may actually decrease, the occurrence of these problems in women with this
condition.Colchicine has causing birth defects and other problems in animal studies.
Breast-feeding problem
Colchicine passes into breast milk. When breast-feeding
mothers receive preventive treat with one 0.6-milligram - mg tablet twice
a day, the amount that appears in the breast milk is not likely to cause problems
in nursing babies. There is no information about whether colchicine can cause
problems in nursing babies when the mother takes larger amounts of it. Mothers
who are taking this drug and who wish to breast-feed must discuss this
with their family doctor.
Use for Children
Studies on the effects of colchicine in diseaseds
with gout have been done only in adults. Gout is very rare in child. However,
colchicine is using in child 3 years of age and older who need preventive
treat for other medical conditions. It has not been reported to cause
various side effects or problems in these children than it does in adults.
Elderly care
Elderly people are especially sensitive to the effects
of colchicine. Always colchicine may stay in the body longer in older diseaseds
than it does in adults people. This may increase the risk of side effects
during treat.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
colchicine, it is especially important that your health care professional
know if you are taking any of the following:
-
Amphotericin B by injection - Fungizone
-
Antineoplastics - cancer drug
-
Antithyroid agents - drug for overactive thyroid
-
Azathioprine - Imuran
-
Chloramphenicol - Chloromycetin
-
Cyclophosphamide - Cytoxan
-
Flucytosine - Ancobon
-
Ganciclovir - Cytovene
-
Interferon - Intron A, Roferon-A
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Phenylbutazone - Butazolidin
-
Plicamycin - Mithracin
-
Zidovudine - Retrovir The risk of serious side effects
causing by a decrease in the numbers of certain blood cells may be increased
Other Information for using
The presence of other medical
problems may effect the use of colchicine. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Alcohol abuse
-
Intestinal disease
-
Stomach ulcer or other stomach problems The risk of stomach
upset may be increased. Always colchicine can make some kinds of stomach or
intestinal problems worse
-
Heart disease
-
Kidney disease
-
Liver disease The risk of serious side effects may be increased
because these conditions can cause colchicine to build up in the body
-
Low white blood cell count
-
Low platelet count The risk of serious side effects may be
increased because colchicine can make these conditions worse
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