Clonidine and Chlorthalidone - Systemic
Brand Names
Combipres
Clonidine and Chlorthalidone *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For clonidine and chlorthalidone,
the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to clonidine - oral or skin patch form, chlorthalidone,
sulfonamides - sulfa drugs, or other thiazide diuretics - water pills. Also
tell your health care professional if you are allergic to any other substance,
such as foods, preservatives, or dyes.
Pregnancy care
Clonidine has not been studied in pregnant women.
However, studies in pets have shown that clonidine does not cause birth
defects but does cause other harmful effects in the fetus. When chlorthalidone
is using during pregnancy, it may cause side effects including jaundice, blood
problems and low potassium in the newborn infant. Be sure you have discussed
this with your family doctor before taking this drug.
Breast-feeding problem
Both clonidine and chlorthalidone pass into breast
milk. Chlorthalidone may decrease the flow of breast milk. Therefore, you
must avoid use of clonidine and chlorthalidone combination during the first
month of breast-feeding.
Use for Children
Studies on this drug have been done only in adult
diseaseds and there is no special info comparing use of clonidine
and chlorthalidone combination in child with use in other age groups. However,
children may be more sensitive than adults to clonidine. Clonidine overdose
has been reported when children accidentally took this drug.
Elderly care
Dizziness or lightheadedness and signs of too much
potassium loss may be more likely to occur in the elderly, who are more sensitive
to the effects of clonidine and chlorthalidone.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
clonidine and chlorthalidone, it is especially important that your health
care professional know if you are taking any of the following:
-
Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol
" Tenormin ", betaxolol " Kerlone ", bisoprolol " Zebeta ", carteolol
" Cartrol ", labetalol " Normodyne ", metoprolol " Lopressor ",
nadolol " Corgard ", oxprenolol " Trasicor ", penbutolol " Levatol ",
pindolol " Visken ", propranolol " Inderal ", sotalol " Betapace,
Sotacor ", timolol " Blocadren " These medication may increase the
risk of harmful effects when clonidine and chlorthalidone combination treat
is stopped suddenly
-
Cholestyramine
-
Colestipol Use with clonidine and chlorthalidone combination
may prevent the chlorthalidone portion of the drug from help you;
take clonidine and chlorthalidone combination at least 1 hour before or 4
hours after cholestyramine or colestipol
-
Digitalis glycosides - heart drug This drug may cause
low potassium in the blood, which may increase the risk of side effects
of digitalis glycosides
-
Lithium - Lithane Use with clonidine and chlorthalidone
combination may cause high blood levels of lithium, which may increase the
risk of side effects
-
Tricyclic antidepressants - amitriptyline " Elavil ", amoxapine
" Asendin ", clomipramine " Anafranil ", desipramine " Pertofrane ",
doxepin " Sinequan ", imipramine " Tofranil ", nortriptyline "
Aventyl ", protriptyline " Vivactil ", trimipramine " Surmontil " These
medication may decrease the effects of clonidine and chlorthalidone combination
on blood pressure
Other Information for using
The presence of other medical
problems may effect the use of clonidine and chlorthalidone. Make sure you
tell your family doctor if you have any other medical problems, especially:
-
Diabetes mellitus - sugar diabetes This drug may change
the amount of diabetes drug needed
-
Gout This drug may increase the amount of uric acid in
the blood, which can lead to gout
-
Heart or blood vessel disease
-
Lupus erythematosus - history of
-
Mental depression - history of
-
Pancreatitis - inflammation of the pancreas
-
Raynaud's syndrome This drug may make these conditions
worse
-
Kidney disease Effects of this drug may be increased because
of slower removal from the body. If kidney disease is severe, the chlorthalidone
portion of this drug may not work
-
Liver disease If this drug causes loss of too much water
from the body, liver disease can become much worse
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