Cisplatin : Before Using - Platinol, Platinol-AQ

Cisplatin - Systemic

Brand Names

Platinol, Platinol-AQ Cisplatin *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For cisplatin, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to cisplatin.

Pregnancy care

There is a risk that this drug may cause birth defects if either the male or female is taking it at the time of conception or if it is taken during pregnancy. Cisplatin causes toxic or harmful effects in the fetus and birth defects in mice. In addition, many cancer medication may cause sterility which could be permanent. Although sterility has not been reported with this drug, the possibility must be kept in mind.

Be sure that you have discussed this with your family doctor before receiving this drug. It is best to use some kind of birth control while you are receiving cisplatin. Tell your family doctor right away if you think you have become pregnant while receiving cisplatin.

Breast-feeding problem

Because cisplatin may cause serious side effects, breast-feeding is generally not recommended while you are receiving it.

Use for Children

Hearing problems and loss of balance are more likely to occur in child, who are usually more sensitive to the effects of cisplatin.

Elderly care

Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no special info comparing use of cisplatin in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are receiving cisplatin, it is especially important that your health care professional know if you are taking any of the following:

Amphotericin B by injection - Fungizone
Antithyroid agents - drug for overactive thyroid
Azathioprine - Imuran
Chloramphenicol - Chloromycetin
Colchicine
Flucytosine - Ancobon
Ganciclovir - Cytovene
Interferon - Introl A, Roferon-A
Plicamycin - Mithracin
Zidovudine - AZT, Retrovir
If you have ever been treated with radiation or cancer medication Cisplatin may increase the side effects of medication or radiation therapy on the blood

Anti-infectives by mouth or by injection - drug for infection
Chloroquine - Aralen
Combination pain drug containing acetaminophen and aspirin - Excedrin or other salicylates - with large amounts taken regularly
Cyclosporine - Sandimmune
Deferoxamine - Desferal - with long-term use
Gold salts - drug for arthritis
Hydroxychloroquine - Plaquenil
Inflammation or pain drug, except narcotics
Lithium - Lithane
Penicillamine - Cuprimine
Plicamycin - Mithracin
Quinine - Quinamm
Tiopronin - Thiola chance of ear and kidney problems causing by cisplatin is increased

Probenecid - Benemid
Sulfinpyrazone - Anturane Cisplatin may raise the amount of uric acid in the blood. Since these medication are using to lower uric acid levels, they may not work as well in diseaseds receiving cisplatin

Other Information for using

The presence of other medical problems may effect the use of cisplatin. Make sure you tell your family doctor if you have any other medical problems, especially:

Chickenpox - including recent exposure
Herpes zoster - shingles chance of severe disease effecting other parts of the body

Gout - history of
Kidney stones - history of Cisplatin may increase levels of uric acid in the body, which can cause gout or kidney stones

Hearing problems May be worsened by cisplatin

Infection Cisplatin decreases your body's ability to fight infection

Kidney disease Effects of cisplatin may be increased because of slower removal from the body