Calcium Channel Blocking Agents - Systemic
Calcium Channel Blocking Agents *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For the calcium channel
blocking agents, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to amlodipine, bepridil, diltiazem, felodipine, flunarizine,
isradipine, nicardipine, nifedipine, nimodipine, or verapamil. Also tell your
health care professional if you are allergic to any other substances, such
as foods, preservatives, or dyes.
Pregnancy care
Calcium channel blocking agents have not been studied
in pregnant women. However, studies in pets have shown that large doses
of calcium channel blocking agents cause birth defects, prolonged pregnancy,
poor bone development in the offspring and stillbirth.
Breast-feeding problem
Although bepridil, diltiazem, nifedipine, verapamil,
and possibly other calcium channel blocking agents, pass into breast milk,
they have not been reported to cause problems in nursing babies.
Use for Children
Although there is no special info comparing
use of this drug in child with use in other age groups, it is not expected
to cause various side effects or problems in child than it does in adults.
Elderly care
Elderly people may be especially sensitive to the
effects of calcium channel blocking agents. This may increase the risk of
side effects during treat. A lower starting dose may be required.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When taking calcium
channel blocking agents it is especially important that your health care professional
know if you are taking any of the following:
-
Acetazolamide - Diamox
-
Amphotericin B by injection - Fungizone
-
Corticosteroids - cortisone-like drug
-
Dichlorphenamide - Daranide
-
Diuretics - water pills
-
Methazolamide - Naptazane These medication can cause hypokalemia
- low levels of potassium in the body, which can increase the unwanted effects
of bepridil
-
Beta-adrenergic blocking agents - acebutolol " Sectral ", atenolol
" Tenormin ", betaxolol " Kerlone ", carteolol " Cartrol ", labetalol
" Normodyne ", metoprolol " Lopressor ", nadolol " Corgard ",
oxprenolol " Trasicor ", penbutolol " Levatol ", pindolol " Visken ",
propranolol " Inderal ", sotalol " Sotacor ", timolol " Blocadren " Effects
of both may be increased. In addition, unwanted effects may occur if a calcium
channel blocking agent or a beta-blocking agent is stopped suddenly after
both have been using together
-
Carbamazepine - Tegretol
-
Cyclosporine - Sandimmune
-
Procainamide - Pronestyl
-
Quinidine - Quinidex Effects of these medication may be
increased if they are using with some calcium channel blocking agents
-
Digitalis glycosides - heart drug Effects of these medication
may be increased if they are using with some calcium channel blocking agents
-
Disopyramide - Norpace Effects of some calcium channel
blocking agents on the heart may be increased
-
Grapefruit juice Effects of felodipine may be increased. No
effects on amlodipine.
Always tell your health care professional if you are using any of the following
medication in the eye:
-
Betaxolol - Betoptic
-
Levobunolol - Betagan
-
Metipranolol - OptiPranolol
-
Timolol - Timoptic Effects on the heart and blood pressure
may be increased
Other Information for using
The presence of other medical
problems may effect the use of the calcium channel blocking agents. Make sure
you tell your family doctor if you have any other medical problems, especially:
-
Congestive heart failure Calcium channel blocking agents may
make this condition worse
-
Heart rhythm problems - history of Bepridil can cause serious
heart rhythm problems
-
Kidney disease
-
Liver disease Effects of the calcium channel blocking agent
may be increased
-
Mental depression - history of Flunarizine may cause mental
depression
-
Parkinson's disease or similar problems Flunarizine can cause
parkinsonian-like effects
-
Other heart or blood vessel disorders Calcium channel blocking
agents may make some heart conditions worse
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