Busulfan - Systemic
Brand Names
Myleran, Busulfex
Busulfan *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding
to use a drug, the chance of taking the drug must be weighed against
the good it will do. This is a decision you will make. For
busulfan, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to busulfan.
Pregnancy care
Although only one case has been reported, there is
a risk that this drug may cause birth defects if either the male or
the female is taking it at the time of conception or if it is taken during
pregnancy. In addition, many cancer medication may cause sterility which could
be permanent. Sterility may occur with busulfan and the possibility must
be kept in mind.Be sure that you have discussed this with your family doctor before taking this
drug. It is best to use some kind of birth control while you are taking
busulfan. Tell your family doctor right away if you think you have become pregnant
while taking busulfan.
Breast-feeding problem
It is not known whether busulfan passes into breast
milk. However, because this drug may cause serious side effects, breast-feeding
is generally not recommended while you are taking it.
Use for Children
Although there is no special info comparing
use of busulfan in child with use in other age groups, this drug is
not expected to cause various side effects or problems in child than
it does in adults.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. Although there is no special info
comparing use of busulfan in the elderly with use in other age groups, this
drug is not expected to cause various side effects or problems in older
people than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When taking busulfan
it is especially important that your health care professional know if you
are taking any of the following:
-
Acetaminophen - Tylenol
-
Acyclovir - Zovirax
-
Amphotericin B by injection - Fungizone
-
Anticonvulsants - seizure drug
-
Antidiabetics, oral - diabetes drug you take by mouth
-
Anti-infectives by mouth or by injection - drug for infection
-
Antineoplastics - cancer drug
-
Antipsychotics - drug for mental illness
-
Antithyroid agents - drug for overactive thyroid
-
Azathioprine - Imuran
-
Captopril - Capoten
-
Carbamazepine - Tegretol
-
Chloramphenicol - Chloromycetin
-
Colchicine
-
Cyclophosphamide - Cytoxan
-
Enalapril - Vasotec
-
Flecainide - Tambocor
-
Flucytosine - Ancobon
-
Ganciclovir - Cytovene
-
Gold salts - drug for arthritis
-
Imipenem and Cilastatin - Primaxin
-
Inflammation or pain drug, except narcotics
-
Interferon - Intron A, Roferon-A
-
Itraconazole - Sporanox
-
Lisinopril - Prinivil, Zestril
-
Maprotiline - Ludiomil
-
Mercaptopurine - Purinethol
-
Methotrexate - Rheumatrex
-
Penicillamine - Cuprimine
-
Pimozide - Orap
-
Plicamycin - Mithracin
-
Procainamide - Pronestyl
-
Promethazine - Phenergan
-
Ramipril - Altace
-
Sulfasalazine - Azulfidine
-
Tocainide - Tonocard
-
Tricyclic antidepressants - drug for depression
-
Trimeprazine - Temaril
-
Zidovudine - AZT, Retrovir
-
If you have ever been treated with radiation or cancer medication Busulfan
may increase the side effects of medication or radiation therapy on the blood
-
Probenecid - Benemid
-
Sulfinpyrazone - Anturane Busulfan may raise the amount
of uric acid in the blood. Since these medication are using to lower uric acid
levels, they may not be as effective in diseaseds taking busulfan
Other Information for using
The presence of other medical
problems may effect the use of busulfan. Make sure you tell your family doctor if
you have any other medical problems, especially:
-
Chickenpox - including recent exposure
-
Herpes zoster - shingles chance of severe disease effecting other
parts of the body
-
Gout - history of
-
Kidney stones - or history of Busulfan may increase levels
of uric acid in the body, which can cause gout or kidney stones
-
Head injury
-
Convulsions - seizures, history of Busulfan injection and very
high doses of oral busulfan can cause convulsions - seizures
-
Infection Busulfan may decrease your body's ability to fight
infection
-
Thalassemia Busulfan may cause increased pressure within the
heart in child
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