Busulfan : Before Using - Myleran, Busulfex

Busulfan - Systemic

Brand Names

Myleran, Busulfex Busulfan *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to use a drug, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For busulfan, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to busulfan.

Pregnancy care

Although only one case has been reported, there is a risk that this drug may cause birth defects if either the male or the female is taking it at the time of conception or if it is taken during pregnancy. In addition, many cancer medication may cause sterility which could be permanent. Sterility may occur with busulfan and the possibility must be kept in mind.

Be sure that you have discussed this with your family doctor before taking this drug. It is best to use some kind of birth control while you are taking busulfan. Tell your family doctor right away if you think you have become pregnant while taking busulfan.

Breast-feeding problem

It is not known whether busulfan passes into breast milk. However, because this drug may cause serious side effects, breast-feeding is generally not recommended while you are taking it.

Use for Children

Although there is no special info comparing use of busulfan in child with use in other age groups, this drug is not expected to cause various side effects or problems in child than it does in adults.

Elderly care

Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people. Although there is no special info comparing use of busulfan in the elderly with use in other age groups, this drug is not expected to cause various side effects or problems in older people than it does in adults people.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When taking busulfan it is especially important that your health care professional know if you are taking any of the following:

Acetaminophen - Tylenol
Acyclovir - Zovirax
Amphotericin B by injection - Fungizone
Anticonvulsants - seizure drug
Antidiabetics, oral - diabetes drug you take by mouth
Anti-infectives by mouth or by injection - drug for infection
Antineoplastics - cancer drug
Antipsychotics - drug for mental illness
Antithyroid agents - drug for overactive thyroid
Azathioprine - Imuran
Captopril - Capoten
Carbamazepine - Tegretol
Chloramphenicol - Chloromycetin
Colchicine
Cyclophosphamide - Cytoxan
Enalapril - Vasotec
Flecainide - Tambocor
Flucytosine - Ancobon
Ganciclovir - Cytovene
Gold salts - drug for arthritis
Imipenem and Cilastatin - Primaxin
Inflammation or pain drug, except narcotics
Interferon - Intron A, Roferon-A
Itraconazole - Sporanox
Lisinopril - Prinivil, Zestril
Maprotiline - Ludiomil
Mercaptopurine - Purinethol
Methotrexate - Rheumatrex
Penicillamine - Cuprimine
Pimozide - Orap
Plicamycin - Mithracin
Procainamide - Pronestyl
Promethazine - Phenergan
Ramipril - Altace
Sulfasalazine - Azulfidine
Tocainide - Tonocard
Tricyclic antidepressants - drug for depression
Trimeprazine - Temaril
Zidovudine - AZT, Retrovir
If you have ever been treated with radiation or cancer medication Busulfan may increase the side effects of medication or radiation therapy on the blood

Probenecid - Benemid
Sulfinpyrazone - Anturane Busulfan may raise the amount of uric acid in the blood. Since these medication are using to lower uric acid levels, they may not be as effective in diseaseds taking busulfan

Other Information for using

The presence of other medical problems may effect the use of busulfan. Make sure you tell your family doctor if you have any other medical problems, especially:

Chickenpox - including recent exposure
Herpes zoster - shingles chance of severe disease effecting other parts of the body

Gout - history of
Kidney stones - or history of Busulfan may increase levels of uric acid in the body, which can cause gout or kidney stones

Head injury
Convulsions - seizures, history of Busulfan injection and very high doses of oral busulfan can cause convulsions - seizures

Infection Busulfan may decrease your body's ability to fight infection
Thalassemia Busulfan may cause increased pressure within the heart in child