Bosentan : Before Using

Bosentan - Systemic

Brand Names

Tracleer Bosentan *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the problems of uses this drugs must be weighed against the good it will do. This is a decision you will make. For bosentan, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to bosentan. Also tell your family doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

Bosentan is not recommended during pregnancy. It has been shown to cause serious birth defects or other problems in pets. Be sure you have discussed this with your family doctor.

Monthly pregnancy tests are needed and a gynecologist must help to decide what contraceptives must be using. Your family doctor must be notified immediately if there is any delay in the start of your menstrual cycle, and any other reason to think that you may be pregnant.

Breast-feeding problem

It is not known whether bosentan passes into breast milk. Although most medication pass into breast milk in small amounts, many of them may be using safely while breast-feeding. Mothers who are using this drug and who wish to breast-feed must discuss this with their family doctor.

Use for Children

Studies on this drug have been done only in adult diseaseds and there is no special info comparing use of bosentan in child with use in other age groups.

Elderly care

Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no special info comparing use of bosentan in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription - over-the-counter "OTC " drug. When you are taking bosentan, it is especially important that your family doctor and pharmacist know if you are taking any of the following:

Cyclosporin A - Neoral or
Use of this drug with bosentan can cause both medication to not work properly

Cytochrome P450 inhibitors - Ketoconazole These medication may increase the effects of bosentan

Hormonal Contraceptives that are implantable - NuvaRing, injectable - Lunelle, or oral - Triphasil Bosentan may prevent contraceptives from help you and may result in an unplanned pregnancy

Hypoglycemic agents, oral - Glyburide Use of this drug with bosentan can cause both medication to not work properly

Statins, such as:
Atorvastatin - e.g. Lipitor or
Lovastatin - Mevacor or
Simvastatin - e.g. Zocor bosentan may decrease the effects of these medication

Other Information for using

The presence of other medical problems may effect the use of bosentan. Make sure you tell your family doctor if you have any other medical problems, especially:

Liver disease bosentan may make make these conditions worse in diseaseds who have moderate or severe liver disease