Bortezomib - Systemic
Brand Names
Velcade
Bortezomib *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
How to Use
Dosage
The dose of bortezomib will be various for various diseaseds.
Follow your family doctor's orders or the directions on the
label
. The following information includes only the average doses of
bortezomib. If you have any questions about the proper dose of bortezomib,
ask your family doctor.
-
For injection
dosage form
-
For treat of multiple myeloma
-
Adults
-
Patients without symptoms or with Grade 1 symptoms of peripheral
neuropathy - paresthesias andloss of reflexes without pain or loss of function 1.3
milligrams - mg per m
twice weekly for two
weeks - days 1, 4, 8 and 11 followed by a 10-day rest period - days
12-21. At least 72 hours must elapse between consecutive dose.
-
Patients with Grade 1 with pain or Grade 2 symptoms of peripheral
neuropathy - interfering with function but not with activities of daily living 1
milligram - mg per m
twice weekly for two
weeks - days 1, 4, 8 and 11 followed by a 10-day rest period - days
12-21. At least 72 hours must elapse between consecutive dose.
-
Patients with Grade 2 with pain or Grade 3 symptoms of peripheral
neuropathy - interfering with activities of daily living Your family doctor
will withhold therapy until toxicity resolves. When toxicity resolves your
family doctor will reduce your dose to 0.7 mg/m
once per week.
-
Patients with Grade 4 symptoms of peripheral neuropathy - permanent
sensory loss that interferes with function Your family doctor will discontinue
therapy
-
Children Bortezomib is not usually recommended in child.
Missed dose Discuss with your family doctor what to do
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