Brand Names

How to Use

Dosage

• For injection dosage form
  • For treat of multiple myeloma
    • Adults
      • Patients without symptoms or with Grade 1 symptoms of peripheral neuropathy - paresthesias andloss of reflexes without pain or loss of function 1.3 milligrams - mg per m twice weekly for two weeks - days 1, 4, 8 and 11 followed by a 10-day rest period - days 12-21. At least 72 hours must elapse between consecutive dose.
      • Patients with Grade 1 with pain or Grade 2 symptoms of peripheral neuropathy - interfering with function but not with activities of daily living 1 milligram - mg per m twice weekly for two weeks - days 1, 4, 8 and 11 followed by a 10-day rest period - days 12-21. At least 72 hours must elapse between consecutive dose.
      • Patients with Grade 2 with pain or Grade 3 symptoms of peripheral neuropathy - interfering with activities of daily living Your family doctor will withhold therapy until toxicity resolves. When toxicity resolves your family doctor will reduce your dose to 0.7 mg/m once per week.
      • Patients with Grade 4 symptoms of peripheral neuropathy - permanent sensory loss that interferes with function Your family doctor will discontinue therapy
    • Children Bortezomib is not usually recommended in child.

Missed dose Discuss with your family doctor what to do