Beta-adrenergic Blocking Agents and Thiazide Diuretics - Systemic
Beta-adrenergic Blocking Agents and Thiazide Diuretics *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For the beta-blocker
and thiazide diuretic combinations, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to beta-blockers, sulfonamides - sulfa drugs, bumetanide,
furosemide, acetazolamide, dichlorphenamide, methazolamide, or any of the
thiazide diuretics. Also tell your health care professional if you are allergic
to any other substances, such as foods, preservatives, or dyes.
Pregnancy care
Use of some beta-blockers during pregnancy has been
associated with low blood sugar, breathing problems, a slower heart rate,
and low blood pressure in the newborn infant. Other reports have not shown
unwanted effects in the newborn infant. Animal studies have shown some beta-blockers
to cause problems in pregnancy when using in doses many times the usual human
dose.Studies with thiazide diuretics have not been done in pregnant women. However,
use of thiazide diuretics during pregnancy may cause side effects such as
jaundice, blood problems and low potassium in the newborn infant. Animal
studies have not shown thiazide diuretic medication to cause birth defects
even when using in doses few times the usual human dose.
Before taking a beta-blocker and thiazide diuretic combination, make sure
your family doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding problem
Atenolol, metoprolol, nadolol, propranolol, pindolol,
timolol and thiazide diuretics pass into breast milk. It is not known whether
bisoprolol passes into breast milk. Thiazide diuretics may decrease the flow
of breast milk.
Use for Children
Although there is no special info comparing
use of this combination drug in child with use in other age groups,
this drug is not expected to cause various side effects or problems
in child than it does in adults. However, extra caution may be necessary
in infants with jaundice, because these medication can make the condition worse.
Elderly care
Some side effects, especially dizziness or lightheadedness
and signs and symptoms of too much potassium loss, may be more likely to occur
in the elderly, who are usually more sensitive to the effects of this drug.
Always beta-blockers may reduce tolerance to cold temperatures in elderly diseaseds.
Drug interactions
Although certain medication must not be using
together at all, in other cases 2 various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
beta-blocker and thiazide diuretic combinations, it is especially important
that your health care professional know if you are taking any of the following:
-
Allergy shots
-
Allergy skin tests The beta-blocker contained in this drug
may increase the risk of a serious allergy to these medication
-
Aminophylline - Somophyllin
-
Caffeine - NoDoz
-
Dyphylline - Lufylline
-
Oxtriphylline - Choledyl
-
Theophylline - Somophyllin-T The side effects of medication
and beta-blockers may be blocked; in addition, theophylline levels in the
body may be increased, especially in diseaseds who smoke
-
Antidiabetics, oral - diabetes drug you take by mouth
-
Insulin There is an increased risk of hyperglycemia - high blood
sugar; the beta-blocker contained in this drug may also cover up certain
symptoms of hypoglycemia - low blood sugar, such as increases in pulse rate
and blood pressure and may make the hypoglycemia last longer
-
Calcium channel blockers - amlodipine " Norvasc ", bepridil "
Bepadin ", diltiazem " Cardizem ", felodipine " Plendil ", flunarizine
" Sibelium ", isradipine " DynaCirc ", nicardipine " Cardene ",
nifedipine " Procardia ", nimodipine " Nimotop ", verapamil "
Calan "
-
Clonidine - Catapres
-
Guanabenz - Wytensin Effects on blood pressure may be
increased. In addition, unwanted effects may occur if clonidine, guanabenz,
or a beta-blocker are stopped suddenly after use together. Unwanted effects
on the heart may occur when beta-blocker and thiazide diuretic combinations
are using with calcium channel blockers
-
Cocaine Cocaine may block the effects of beta-blockers; in
addition, there is an increased risk of high blood pressure, fast heartbeat,
and possibly heart problems if you use cocaine while taking a beta-blocker
and thiazide diuretic combination
-
Digitalis glycosides - heart drug Use with beta-blocker
and thiazide diuretic combinations may cause high blood levels of digoxin,
which may increase the risk of side effects
-
Lithium The thiazide diuretic contained in this combination
may cause high blood levels of lithium, which may increase the risk of side
effects
-
Monoamine oxidase - MAO inhibitors - furazolidone " Furoxone ",
isocarboxazid " Marplan ", phenelzine " Nardil ", procarbazine "
Matulane ", selegiline " Eldepryl ", tranylcypromine " Parnate " Taking
a beta-blocker and thiazide diuretic combination while you are taking or within
2 weeks of taking monoamine oxidase - MAO inhibitors may cause severe high
blood pressure
Other Information for using
The presence of other medical
problems may effect the use of the beta-blockers and thiazide diuretics. Make
sure you tell your family doctor if you have any other medical problems, especially:
-
Allergy, history of - asthma, eczema, hay fever, hives,
-
Bronchitis
-
Emphysema This combination drug may make allergys
to other substances more severe or make the reaction last longer; in addition,
the beta-blocker contained in this combination can increase trouble in breathing
-
Bradycardia - unusually slow heartbeat
-
Heart or blood vessel disease This combination drug may
make these heart problems worse; also, if treat is stopped suddenly, unwanted
effects may occur
-
Diabetes mellitus - sugar diabetes The beta-blocker contained
in this drug may cause hyperglycemia - high blood sugar and circulation
problems; in addition, if your diabetes drug causes your blood sugar to
be too low, beta-blockers may cover up some of the symptoms - fast heartbeat,
although they will not cover up other symptoms such as dizziness or sweating;
the thiazide diuretic contained in this drug may increase the amount of
sugar in the blood
-
Gout - history of
-
Lupus erythematosus - history of
-
Pancreatitis - inflammation of the pancreas The thiazide diuretic
contained in this drug may make these conditions worse
-
Kidney disease
-
Liver disease Effects of this drug may be increased because
of slower removal from the body
-
Mental depression - or history of
-
Myasthenia gravis
-
Pheochromocytoma
-
Psoriasis
-
Raynaud's syndrome The beta-blocker contained in this drug
may make these conditions worse
-
Overactive thyroid Stopping this drug suddenly may increase
symptoms of overactive thyroid; the beta-blocker contained in this drug
may cover up fast heartbeat, which is a sign of overactive thyroid
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