Barbiturates, Aspirin and Codeine : Before Using

Barbiturates, Aspirin and Codeine - Systemic

Barbiturates, Aspirin and Codeine *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

In deciding to using a medication, the chance of taking the drug must be weighed against the good it will do. This is a decision you will make. For barbiturate, aspirin, and codeine combinations, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to aspirin or other salicylates including methyl salicylate - oil of wintergreen; butalbital, phenobarbital, or other barbiturates; caffeine; codeine; or any of the following medication:

Diclofenac - Voltaren
Diflunisal - Dolobid
Etodolac - Lodine
Fenoprofen - Nalfon
Floctafenine - Idarac
Flurbiprofen, oral - Ansaid
Ibuprofen - Motrin
Indomethacin - Indocin
Ketoprofen - Orudis
Ketorolac - Toradol
Meclofenamate - Meclomen
Mefenamic acid - Ponstel
Nabumetone - Relafen
Naproxen - Naprosyn
Oxaprozin - Daypro
Oxyphenbutazone - Tandearil
Phenylbutazone - Butazolidin
Piroxicam - Feldene
Sulindac - Clinoril
Suprofen - Suprol
Tenoxicam - Mobiflex
Tiaprofenic acid - Surgam
Tolmetin - Tolectin
Zomepirac - Zomax

Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

For butalbital or phenobarbital : Barbiturates have been shown to increase the risk of birth defects. Always one study has suggested that barbiturates taken during pregnancy may increase the risk of brain tumors in the baby. Barbiturates may cause breathing problems in the newborn baby if taken just before or during delivery.
For aspirin : Although studies have not shown that aspirin causes birth defects, aspirin has causing birth defects in animal studies.
Do not take aspirin during the last 3 months of pregnancy unless it has been ordered by your family doctor . Some reports have suggested that use of aspirin late in pregnancy may cause a decrease in the newborn's weight and possible death of the fetus or newborn baby. However, the mothers in these reports had been taking much larger amounts of aspirin than are usually recommended. Studies of mothers taking aspirin in the doses that are usually recommended did not show these unwanted effects.
There is a risk that regular use of aspirin late in pregnancy may cause unwanted effects on the heart or blood flow in the fetus or in the newborn baby. Always use of aspirin during the last 2 weeks of pregnancy may cause bleeding problems in the fetus before or during delivery or in the newborn baby. In addition, too much use of aspirin during the last 3 months of pregnancy may increase the length of pregnancy, prolong labor, cause other problems during delivery, or cause severe bleeding in the mother before, during, or after delivery.
For codeine : Although studies on birth defects with codeine have not been done in pregnant women, it has not been reported to cause birth defects. However, it may cause breathing problems in the newborn baby if taken just before or during delivery. Codeine did not cause birth defects in animal studies, but it causing slower development of bones and other harmful effects in the fetus.
For caffeine : Studies have not shown that caffeine causes birth defects. However, use of large amounts of caffeine during pregnancy may cause problems with the heart rhythm and the growth of the fetus. Always studies in pets have shown that caffeine causes birth defects when given in very large doses - amounts equal to those in 12 to 24 cups of coffee a day.

Breast-feeding problem

Although this combination drug has not been reported to cause problems, the risk always exists, especially if the drug is taken for a long time or in large amounts.

For butalbital or phenobarbital : Barbiturates pass into the breast milk and may cause drowsiness, unusually slow heartbeat, shortness of breath, or troubled breathing in nursing babies.
For aspirin : Aspirin passes into the breast milk. However, taking aspirin in the amount present in these combination medication has not been reported to cause problems in nursing babies.
For codeine : Codeine passes into the breast milk in small amounts. However, it has not been reported to cause problems in nursing babies.
For caffeine : The caffeine in the butalbital, aspirin and codeine combination drug passes into the breast milk in small amounts. Taking caffeine in the amounts present in this combination drug has not been reported to cause problems in nursing babies. However, studies have shown that nursing babies may appear jittery when their mothers drink large amounts of caffeine-containing beverages. Therefore, breast-feeding mothers who use caffeine-containing medication must probably limit the amount of caffeine they take in from other medication or from beverages.

Use for Children

For butalbital or phenobarbital : Although barbiturates often cause drowsiness, some children become excited after taking them.
For aspirin: Do not give a drug containing aspirin to a child with fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's family doctor . This is very important because aspirin may cause a serious illness called Reye's syndrome in child with fever causing by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the risk of side effects during treat.
For caffeine : There is no special info comparing use of caffeine in child up to 12 years of age with use in other age groups. However, caffeine is not expected to cause various side effects or problems in child than it does in adults.

Adolescents Teenagers with fever or other symptoms of a virus infection, especially flu or chickenpox, must check with a family doctor before taking this drug . The aspirin in this combination drug may cause a serious illness called Reye's syndrome in teenagers with fever causing by a virus infection, especially flu or chickenpox.

Elderly care

For butalbital or phenobarbital : Confusion, depression, or excitement may be especially likely to occur in elderly diseaseds, who are usually more sensitive than adults people to the effects of barbiturates.
For aspirin : Elderly diseaseds are more sensitive than adults people to the effects of aspirin. This may increase the risk of side effects during treat.
For codeine : Breathing problems may be especially likely to occur in elderly diseaseds, who are usually more sensitive than adults people to the effects of codeine.
For caffeine : Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no specific information comparing use of caffeine in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking this combination drug, it is especially important that your health care professional know if you are taking any of the following:

Antacids, large amounts taken regularly, especially calcium- and/or magnesium-containing antacids or sodium bicarbonate - baking soda,
Urinary alkalizers - drug that makes the urine less acid, such as acetazolamide " Diamox ", dichlorphenamide " Daranide ", methazolamide " Neptazane ", potassium or sodium citrate andcitric acid These medication may cause aspirin to be removed from the body faster than usual, which may shorten the length of time that aspirin is effective; acetazolamide, dichlorphenamide and methazolamide may also increase the risk of side effects when taken together with aspirin

Anticoagulants - blood thinners
Heparin Use of these medication together with aspirin may increase the risk of bleeding; also, barbiturates, especially phenobarbital, may decrease the effects of anticoagulants

Antidepressants, tricyclic - amitriptyline " Elavil ", amoxapine " Asendin ", clomipramine " Anafranil ", desipramine " Pertofrane ", doxepin " Sinequan ", imipramine " Tofranil ", nortriptyline " Aventyl ", protriptyline " Vivactil ", trimipramine " Surmontil "
Central nervous system - CNS depressants - medication that often cause drowsiness These medication may add to the effects of barbiturates and codeine and increase the risk of drowsiness or other side effects

Carbamazepine
Contraceptives, oral - birth control pills containing estrogens
Corticosteroids - cortisone-like medication
Corticotropin - ACTH Barbiturates, especially phenobarbital, may make these medication less effective

Divalproex - Depakote
Methotrexate - Mexate
Valproic acid - Depakene
Vancomycin - Vancocin The risk of serious side effects may be increased

Naltrexone - Trexan Naltrexone blocks the pain-relieving effect of codeine

Probenecid - Benemid
Sulfinpyrazone - Anturane Aspirin can keep these medication from help you for treating gout

Other Information for using

The presence of other medical problems may effect the use of butalbital, aspirin and codeine combination. Make sure you tell your family doctor if you have any other medical problems, especially:

Alcohol abuse - or history of
Drug abuse or dependence - or history of Dependence on barbiturates andcodeine may develop

Asthma, especially if occurring together with other allergies and nasal polyps - history of,
Brain disease or head injury
Colitis
Convulsions - seizures - history of
Emphysema or other chronic lung disease
Enlarged prostate or problems with urination
Gallbladder disease or gallstones
Hyperactivity - in child
Kidney disease
Liver disease The risk of serious side effects may be increased

Diabetes mellitus - sugar diabetes
Mental depression
Overactive thyroid
Porphyria - or history of Barbiturates can make these conditions worse

Gout Aspirin can make this condition worse and can also lessen the effects of some medication using to treat gout

Heart disease - severe The caffeine in the butalbital, aspirin, and codeine combination can make some kinds of heart disease worse

Hemophilia or other bleeding problems
Vitamin K deficiency Aspirin increases the risk of serious bleeding

Stomach ulcer, especially with a history of bleeding, or other stomach problems Aspirin can make your condition worse