Atovaquone and Proguanil - Systemic
Brand Names
Malarone
Atovaquone and Proguanil *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For atovaquone and proguanil
, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual
or allergy to atovaquone or proguanil hydrochloride. Also tell your
health care professional if you are allergic to any other substances, such
as preservatives or dyes.
Pregnancy care
Atovaquone and proguanil combination has not been
studied in pregnant women. However, this drug has not been shown to cause
birth defects or other problems in animal studies. Before taking this drug,
make sure your family doctor knows if you are pregnant or if you may become pregnant
It is advisable for pregnant women to avoid traveling to areas where there
is a risk of getting malaria.
Breast-feeding problem
It is not known if atovaquone passes into human
breast milk, but it was found in the milk of rats. Proguanil passes into breast
milk, but in small quantities. Be sure you have discussed the chance and benefits
of this drug with your family doctor.
Use for Children
Studies on this drug have been done only in
diseaseds who weigh more than 25 pounds - 11 kilograms "kg " and there is no
special info comparing use of atovaquone and proguanil combination
in diseaseds of lesser weight.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of atovaquone and proguanil in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using together at all, in other cases
two various medication may be using together even if an interaction might
occur. In these cases, your family doctor may want to change the dose, or other precautions
may be necessary. When you are taking atovaquone and proguanil, it is especially
important that your health care professional know if you are taking any of
the following:
-
Rifampin - Rifadin Use of rifampin may decrease the
amount of atovaquone in the blood and keep it from help you
-
Metoclopramide - Reglan Use of metoclopramide with atovaquone
and proguanil may lessen the amount of atovaquone your body absorbs
-
Tetracycline - Sumycin Use of tetracycline lowers the
amount of atovaquone in your blood.
Other Information for using
The presence of other medical problems may effect the use of atovaquone
and proguanil. Make sure you tell your family doctor if you have any other medical
problems, especially:
-
Diarrhea or vomiting The amount of atovaquone and proguanil
the body can absorb may be decreased.
-
Kidney disease or failure The amount of atovaquone and proguanil
the body can eliminate may be decreased.
-
Return of previously treated malaria Atovaquone and proguanil
may not work in treating the malaria again; your family doctor may need to give
you another type of drug
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