Asparaginase - Systemic
Brand Names
Elspar, Kidrolase, colaspase
Asparaginase *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For asparaginase, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to asparaginase.
Pregnancy care
Asparaginase has not been studied in pregnant women.
However, studies in mice and rats have shown that asparaginase slows the weight
gain of infants and may also increase the risk of birth defects or cause a
decrease in successful pregnancies. In addition, asparaginase has causing birth
defects in rabbits.It is best to use some kind of birth control while you are receiving asparaginase.
Tell your family doctor right away if you think you have become pregnant while receiving
asparaginase.
Breast-feeding problem
It is not known whether asparaginase passes into
breast milk. However, because asparaginase may cause serious side effects,
breast-feeding is generally not recommended while you are receiving it.
Use for Children
This drug has been tested in child and has
not been shown to cause various side effects or problems than it does in
adults. In fact, the side effects of this drug seem to be less severe
in child than in adults.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of asparaginase in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are receiving
asparaginase it is especially important that your health care professional
know if you are taking any of the following:
-
Probenecid - Benemid
-
Sulfinpyrazone - Anturane Asparaginase may raise the
concentration of uric acid in the blood. Since these medication are using to
lower uric acid levels, they may not work as well in diseaseds receiving asparaginase
-
If you have ever been treated with radiation or cancer medication Asparaginase
may increase the total effects of these medications and radiation therapy
Other Information for using
The presence of other medical
problems may effect the use of asparaginase. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Chickenpox - including recent exposure
-
Herpes zoster - shingles chance of severe disease effecting other
parts of the body
-
Diabetes mellitus - sugar diabetes Asparaginase may increase
glucose - sugar in the blood
-
Gout
-
Kidney stones Asparaginase may increase levels of uric acid
in the body, which can cause gout or kidney stones
-
Infection Asparaginase can reduce your body's ability to fight
infection
-
Liver disease Asparaginase may worsen the condition
-
Pancreatitis - inflammation of the pancreas Asparaginase may
cause pancreatitis
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