How to Use

For diseaseds taking a capsule, tablet - including caplet, or liquid form of this drug:

• Take tablet or capsule forms of these medication with a full glass - 8 ounces of water . Always do not lie down for about 15 to 30 minutes after taking the drug. This helps to prevent irritation that may lead to trouble in swallowing.
• To lessen stomach upset, these medication must be taken with food or an antacid. This is especially important when you are taking indomethacin, mefenamic acid, phenylbutazone, or piroxicam, which must always be taken with food or an antacid. Taking the extended-release tablet dosage form of flurbiprofen or naproxen and taking nabumetone with food may also help the drug be absorbed into your body more quickly. However, your family doctor may want you to take the first 1 or 2 doses of other nonsteroidal anti-inflammatory drugs 30 minutes before meals or 2 hours after meals. This helps the drug start working a little faster when you first begin to take it. However, after the first few doses, take the drug with food or an antacid.
• It is not necessary to take delayed-release - enteric-coated tablets with food or an antacid, because the enteric coating helps protect your stomach from the irritating effects of the drug. Always it is not necessary to take ketoprofen extended-release capsules - Oruvail with food or an antacid, because the drug inside the capsules is enteric coated.
• If you will be taking your drug together with an antacid, one that contains magnesium and aluminum hydroxides - Maalox may be the best kind of antacid to use, unless your family doctor has directed you to use another antacid. However, do not mix the liquid form of ibuprofen, indomethacin, or naproxen together with an antacid, or any other liquid, before taking it. To do so may cause the drug to break down. If stomach upset - indigestion, nausea, vomiting, stomach pain, or diarrhea continues or if you have any questions about how you must be taking this drug, check with your health care professional.
• Some of these medication must be swallowed whole. Tablets must not be crushed, chewed, or broken and capsules must not be emptied out, before you take the drug. These include delayed-release - enteric-coated or extended-release tablets or capsules, diflunisal tablets - Dolobid and phenylbutazone tablets - Butazolidin. If you are not sure whether you are taking a delayed-release or extended-release form of your drug, check with your pharmacist.

For diseaseds using a suppository form of this drug:

• If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.
• To insert the suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum.
• Indomethacin suppositories must be kept inside the rectum for at least one hour so that all of the drug can be absorbed by your body. This helps the drug work better.

For diseaseds taking nonprescription - over-the-counter "OTC " ibuprofen or naproxen :

• This drug comes with a patient information sheet. Read it carefully. If you have any questions about this information, check with your health care professional.

For safe and effective use of this drug, do not take more of it, do not take it more often and do not take it for a longer time than ordered by your health care professional or directed on the nonprescription - over-the-counter "OTC " package label . Taking too much of any of these medication may increase the risk of unwanted effects, especially in elderly diseaseds.

When using for severe or continuing arthritis, a nonsteroidal anti-inflammatory drug must be taken regularly as ordered by your family doctor in order for it to help you. These medication usually begin to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Always few weeks may pass before you feel the full effects of the drug.

For diseaseds taking mefenamic acid :

• Always take mefenamic acid with food or antacids .
• Do not take mefenamic acid for more than 7 days at a time unless otherwise directed by your family doctor. To do so may increase the risk of side effects, especially in elderly diseaseds.

For diseaseds taking phenylbutazone :

• Phenylbutazone is intended to treat your current medical problem only Do not take it for any other aches or pains . Always phenylbutazone must be using for the shortest time possible because of the risk of serious side effects, especially in diseaseds who are 40 years of age or older.

Dosage

The number of capsules or tablets or teaspoonfuls of suspension that you take, or the number of suppositories that you use, depends on the strength of the drug. Always the number of doses you take each day, the time allowed between doses and the length of time you take the drug depend on the medical problem for which you are taking the drug .

People with arthritis usually need to take more of a nonsteroidal anti-inflammatory drug during a flare-up than they do between flare-ups of arthritis symptoms. Therefore, your dose may need to be increased or decreased as your condition changes.

For diclofenac
• For tablet dosage form:
  • For relieving pain or menstrual cramps:
    • Adults 50 milligrams - mg three times a day as needed. Your family doctor may direct you to take 100 mg for the first dose only.
    • Children Use and dose must be determined by your family doctor.
  • For rheumatoid arthritis:
    • Adults At first, 50 mg three or four times a day. Your family doctor may increase the dose, if necessary, up to a total of 225 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For osteoarthritis:
    • Adults At first, 50 mg two or three times a day. Usually, no more than a total of 150 mg a day must be taken. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For spondylitis - lower back pain:
    • Adults At first, 25 mg four or five times a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
• For delayed-release tablet dosage form:
  • For rheumatoid arthritis:
    • Adults At first, 50 mg three or four times a day. Your family doctor may increase the dose, if necessary, up to a total of 225 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For osteoarthritis:
    • Adults At first, 50 mg two or three times a day. Usually, no more than a total of 150 mg a day must be taken. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For spondylitis - lower back pain:
    • Adults At first, 25 mg four or five times a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
• For extended-release tablet dosage form:
  • For rheumatoid arthritis, osteoarthritis, or spondylitis:
    • Adults Usually 75 or 100 mg once a day, in the morning or evening. Some people may need 75 mg twice a day, in the morning and evening. Take the drug at the same time every day.
    • Children Use and dose must be determined by your family doctor.
• For rectal dosage form - suppositories:
  • For rheumatoid arthritis, osteoarthritis, or spondylitis:
    • Adults One 50-mg or 100-mg suppository, inserted into the rectum. The suppository is usually using only at night by people who take tablets during the day. Usually, no more than a total of 150 mg of diclofenac must be using in a day from all dosage forms combined.
    • Children Use and dose must be determined by your family doctor.

For diflunisal
• For oral dosage form - tablets:
  • For pain:
    • Adults 1000 milligrams - mg for the first dose, then 500 mg every eight to twelve hours as needed. Some people may need only 500 mg for the first dose, then 250 mg every eight to twelve hours as needed. Usually, no more than a total of 1500 mg a day must be taken.
    • Children Dose must be determined by your family doctor.
  • For rheumatoid arthritis or osteoarthritis:
    • Adults At first, 250 or 500 mg twice a day. Your family doctor may increase the dose, if necessary, up to a total of 1500 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Dose must be determined by your family doctor.

For etodolac
• For oral dosage forms - capsules or tablets:
  • For pain:
    • Adults 400 milligrams - mg for the first dose, then 200 to 400 mg every six to eight hours as needed. Usually, no more than a total of 1200 mg a day must be taken.
    • Children Use and dose must be determined by your family doctor.
  • For osteoarthritis:
    • Adults At first, 400 mg two or three times a day or 300 mg three or four times a day. Usually, no more than a total of 1200 mg a day must be taken. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  
  For extended-release tablet dosage form:
  • For rheumatoid arthritis, osteoarthritis, or spondylitis:
    • Adults Usually 400 to 1000 mg once a day. Take the drug at the same time every day.
    • Children Use and dose must be determined by your family doctor.

For fenoprofen
• For oral dosage forms - capsules or tablets:
  • For pain:
    • Adults 200 milligrams - mg every four to six hours as needed.
    • Children Use and dose must be determined by your family doctor.
  • For arthritis:
    • Adults At first, 300 to 600 mg three or four times a day. Your family doctor may increase the dose, if necessary, up to a total of 3200 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.

For floctafenine
• For oral dosage form - tablets:
  • For pain:
    • Adults 200 to 400 milligrams - mg every six to eight hours, as needed. Usually, no more than 1200 mg a day must be taken.
    • Children Use is not recommended.

For flurbiprofen
• For oral tablet dosage form:
  • For menstrual cramps:
    • Adults 50 milligrams - mg four times a day.
    • Children Use and dose must be determined by your family doctor.
  • For bursitis, tendinitis, or athletic injuries:
    • Adults 50 mg every four to six hours as needed.
    • Children Use and dose must be determined by your family doctor.
  • For rheumatoid arthritis or osteoarthritis:
    • Adults At first, 200 to 300 mg a day, divided into smaller amounts that are taken two to four times a day. Usually, no more than a total of 300 mg a day must be taken. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For spondylitis - lower back pain:
    • Adults At first, 50 mg four times a day. Your family doctor may increase the dose, if necessary, up to a total of 300 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
• For extended-release capsule dosage form:
  • For arthritis:
    • Adults 200 mg once a day, in the evening. Take the drug at the same time every day.
    • Children Use and dose must be determined by your family doctor.

For ibuprofen
• For oral dosage forms - oral suspension, tablets, chewable tablets:
  • For pain or menstrual cramps:
    • Adults and teenagers 200 to 400 milligrams - mg every four to six hours as needed. If you are taking the drug without a prescription from your health care professional, do not take more than a total of 1200 mg - six 200-mg tablets a day.
    • Children up to 12 years of age Use and dose must be determined by your family doctor.
  • For fever:
    • Adults and teenagers 200 to 400 mg every four to six hours as needed. If you are taking the drug without a prescription from your health care professional, do not take more than a total of 1200 mg - six 200-mg tablets a day.
    • Children 6 months to 12 years of age The drug must be using only with a prescription from your family doctor. The dose is based on body weight and on the body temperature. For fevers lower than 102.5 °F - 39.2 °C the dose is 5 mg per kilogram - kg - about 2.2 mg per pound of body weight. For higher fevers the dose is 10 mg per kg - about 4.5 mg per pound of body weight.
    • Infants younger than 6 months of age Use and dose must be determined by your family doctor.
  • For arthritis:
    • Adults and teenagers At first, a total of 1200 to 3200 mg a day, divided into smaller amounts that are taken three or four times a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children 6 months to 12 years of age The dose is based on body weight. At first, a total of 30 to 40 mg per kg - about 13.6 to 18 mg per pound of body weight a day, divided into smaller amounts that are taken three or four times a day. Your family doctor may increase the dose, if necessary, up to a total of 50 mg per kg - about 21 mg per pound of body weight a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Infants younger than 6 months of age Use and dose must be determined by your family doctor.

For indomethacin
• For capsule or oral suspension dosage forms:
  • For arthritis:
    • Adults At first, 25 or 50 milligrams - mg two to four times a day. Your family doctor may increase the dose, if necessary, up to a total of 200 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children The dose is based on body weight. At first, 1.5 to 2.5 mg per kilogram - kg - about 0.7 to 1.1 mg per pound of body weight a day, divided into smaller amounts that are taken three or four times a day. Your family doctor may increase the dose, if necessary, up to a total of 4 mg per kg - about 1.8 mg per pound of body weight or 200 mg a day, whichever is less. After your condition improves your family doctor may direct you to take a lower dose.
  • For gout:
    • Adults 100 mg for the first dose, then 50 mg three times a day. After the pain is relieved, your family doctor may direct you to take a lower dose for a while before stopping treat completely.
    • Children Use and dose must be determined by your family doctor.
  • For bursitis or tendinitis:
    • Adults 25 mg three or four times a day or 50 mg three times a day.
    • Children Use and dose must be determined by your family doctor.
• For extended-release capsule dosage form:
  • For arthritis:
    • Adults 75 mg once a day, in the morning or evening. Some people may need to take 75 mg twice a day, in the morning and evening. Take the drug at the same time each day.
    • Children Dose must be determined by your family doctor.
• For rectal suppository dosage form:
  • For arthritis, bursitis, tendinitis, or gout:
    • Adults One 50-mg suppository, inserted into the rectum up to four times a day.
    • Children One 50-mg suppository, inserted into the rectum up to four times a day. The suppository dosage form is too strong for small children. However, the suppositories may be using for large or heavy children if they need doses as large as 50 mg.

For ketoprofen
• For capsule, tablet, or delayed-release tablet dosage forms:
  • For pain or menstrual cramps:
    • Adults 25 to 50 milligrams - mg every six to eight hours as needed. Some people may need to take as much as 75 mg every six to eight hours. Doses larger than 75 mg are not likely to give better relief.
    • Over-the-counter medication 12.5 mg every 4 to 6 hours.
    • Children Use and dose must be determined by your family doctor.
  • For arthritis:
    • Adults At first, 50 mg four times a day or 75 mg three times a day. Your family doctor may increase the dose, if necessary, up to a total of 300 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
• For extended-release capsule or extended-release tablet dosage forms:
  • For arthritis:
    • Adults 150 or 200 mg once a day, in the morning or evening. Take the drug at the same time every day.
    • Children Use and dose must be determined by your family doctor.
• For rectal suppository dosage form:
  • For arthritis:
    • Adults 50 or 100 mg twice a day, inserted into the rectum, in the morning and evening. Sometimes, the suppository is using only at night by people who take an oral dosage form - capsules or delayed-release tablets during the day. Usually, no more than a total of 300 mg of ketoprofen must be using in a day from all dosage forms combined.
    • Children Use and dose must be determined by your family doctor.

For meclofenamate
• For oral dosage form - capsules:
  • For arthritis:
    • Adults and teenagers 14 years of age and older At first, 50 milligrams - mg four times a day. Your family doctor may increase the dose, if necessary, up to a total of 400 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children up to 14 years of age Use and dose must be determined by your family doctor.
  • For pain:
    • Adults and teenagers 14 years of age and older 50 mg every four to six hours. Some people may need as much as 100 mg every four to six hours.
    • Children up to 14 years of age Use and dose must be determined by your family doctor.
  • For menstrual cramps and heavy menstrual bleeding:
    • Adults and teenagers 14 years of age and older 100 mg three times a day for up to six days.
    • Children up to 14 years of age Use and dose must be determined by your family doctor.

For mefenamic acid
• For oral dosage form - capsules:
  • For pain and for menstrual cramps:
    • Adults and teenagers 14 years of age and older 500 milligrams - mg for the first dose, then 250 mg every six hours as needed for up to seven days.
    • Children up to 14 years of age Use and dose must be determined by your family doctor.

For meloxicam
• For oral dosage form - tablets:
  • For osteoarthritis:
    • Adults 7.5 milligrams - mg daily in a single dose.

For nabumetone
• For oral dosage form - tablets:
  • For arthritis:
    • Adults At first, 1000 milligrams - mg once a day, in the morning or evening, or 500 mg twice a day, in the morning and evening. Your family doctor may increase the dose, if necessary, up to a total of 2000 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.

For naproxen
• For naproxen - Naprosyn tablet, oral suspension, and delayed-release tablet dosage forms:
  • For arthritis:
    • Adults At first, 250, 375, or 500 milligrams - mg two times a day, in the morning and evening. Your family doctor may increase the dose, if necessary, up to a total of 1500 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children The dose is based on body weight. At first, 5 mg per kilogram - kg - about 2.25 mg per pound of body weight twice a day. After your condition improves your family doctor may direct you to take a lower dose.
  • For bursitis, tendinitis, menstrual cramps and other kinds of pain:
    • Adults 500 mg for the first dose, then 250 mg every six to eight hours as needed.
    • Children Use and dose must be determined by your family doctor.
  • For gout:
    • Adults 750 mg for the first dose, then 250 mg every eight hours until the attack is relieved.
    • Children Use and dose must be determined by your family doctor.
• For naproxen extended-release tablet - Naprelan dosage form:
  • For arthritis and pain:
    • Adults 750 to 1000 mg once a day, in the morning or evening.
    • Children The extended-release tablets are too strong for use in child.
• For naproxen - Naprosyn rectal suppository dosage form:
  • For arthritis:
    • Adults One 500-mg suppository, inserted into the rectum at bedtime. The suppository is usually using only at night by people who take an oral dosage form - tablets, oral suspension, or delayed-release tablets during the day. Usually, no more than a total of 1500 mg of naproxen must be using in a day from all dosage forms combined.
    • Children The suppositories are too strong for use in child.
• For naproxen sodium - Aleve, Anaprox tablet dosage form:
  • For arthritis:
    • Adults At first, 275 or 550 mg two times a day, in the morning and evening, or 275 mg in the morning and 550 mg in the evening. Your family doctor may increase the dose, if necessary, up to a total of 1650 mg a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Naproxen sodium tablets are too strong for most children. Naproxen - Naprosyn tablets or oral suspension are usually using for children.
  • For bursitis and tendinitis:
    • Adults 550 mg for the first dose, then 275 mg every six to eight hours as needed.
    • Children Use and dose must be determined by your family doctor. Naproxen sodium tablets are too strong for most children.
  • For gout:
    • Adults 825 mg for the first dose, then 275 mg every eight hours until the attack is relieved.
    • Children Use and dose must be determined by your family doctor. Naproxen sodium tablets are too strong for most children.
  • For pain, fever and menstrual cramps:
    • Adults and children 12 years of age or older For nonprescription - over-the-counter "OTC " use: 220 mg - one tablet every eight to twelve hours as needed. Some people may get better relief if they take 440 mg - two tablets for the first dose, then 220 mg twelve hours later on the first day only. If you are taking this drug without a prescription from your health care professional, do not take more than three 220-mg tablets a day. If you are older than 65 years of age, do not take more than two 220-mg tablets a day. Your health care professional may direct you to take larger doses.
    • Children up to 12 years of age Use and dose must be determined by your family doctor.

For oxaprozin
• For oral dosage form - tablets:
  • For arthritis:
    • Adults At first, 600 milligrams - mg once or twice a day, or 1200 mg once a day. Some people may need a larger amount for the first dose only. Your family doctor may increase the dose, if necessary, up to 1800 mg a day. This large dose must always be divided into smaller amounts that are taken two or three times a day. After your condition improves your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.

For phenylbutazone
• For oral dosage forms - capsules, tablets, and buffered tablets:
  • For severe arthritis:
    • Adults and teenagers 15 years of age and older At first, 100 milligrams - mg three or four times a day. Some people may need a higher dose of 200 mg three times a day. After your condition improves your family doctor may direct you to take a lower dose for a while before stopping treat completely. This drug must not be taken for longer than a few weeks.
    • Children up to 15 years of age Use is not recommended.
  • For gout:
    • Adults 400 mg for the first dose, then 100 mg every four hours for one week or less.
    • Children up to 15 years of age Use is not recommended.

For piroxicam
• For oral dosage form - capsules:
  • For arthritis:
    • Adults 20 milligrams - mg once a day or 10 mg twice a day.
    • Children Dose must be determined by your family doctor.
  • For menstrual cramps:
    • Adults 40 mg once a day for one day only, then 20 mg once a day if needed.
    • Children Dose must be determined by your family doctor.
• For rectal dosage form - suppositories:
  • For arthritis:
    • Adults 20 mg once a day or 10 mg twice a day.
    • Children Dose must be determined by your family doctor.

For sulindac
• For oral dosage form - tablets:
  • For arthritis:
    • Adults At first, 150 or 200 milligrams - mg twice a day. After your condition improves, your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
  • For gout, bursitis, or tendinitis:
    • Adults At first, 200 mg twice a day. After the pain is relieved, your family doctor may direct you to take a lower dose for a while before treat is stopped completely.
    • Children Use and dose must be determined by your family doctor.

For tenoxicam
• For oral dosage form - tablets:
  • For arthritis:
    • Adults and teenagers 16 years of age and older At first, 20 milligrams - mg once a day, at the same time each day. For some people, a smaller dose of 10 mg - one-half tablet a day may be enough.
    • Children and teenagers up to 16 years of age Dose must be determined by your family doctor.

For tiaprofenic acid
• For oral tablet dosage form:
  • For arthritis:
    • Adults At first, 200 milligrams - mg three times a day or 300 mg twice a day. After your condition improves, your family doctor may direct you to take a lower dose.
    • Children Use and dose must be determined by your family doctor.
• For extended-release capsule dosage form:
  • For arthritis:
    • Adults 600 mg - two capsules once a day, at the same time each day.
    • Children Use and dose must be determined by your family doctor.

For tolmetin
• For oral dosage forms - capsules or tablets:
  • For arthritis:
    • Adults At first, 400 milligrams - mg three times a day. Your family doctor may increase the dose, if necessary, up to a total of 1800 mg a day. After your condition improves, your family doctor may direct you to take a lower dose.
    • Children 2 years of age and older The dose is based on body weight. At first, 20 mg per kilogram - kg - about 9 mg per pound of body weight a day, divided into smaller amounts that are taken three or four times a day. Your family doctor may increase the dose, if necessary, up to 30 mg per kg - about 13.5 mg per pound of body weight a day. After your condition improves, your family doctor may direct you to take a lower dose.
    • Children up to 2 years of age Dose must be determined by your family doctor.

Missed dose If your health care professional has ordered you to take this drug according to a regular schedule and you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. - For long-acting medication or extended-release dosage forms that are only taken once or twice a day, take the missed dose only if you remember within an hour or two after the dose must have been taken. If you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage To store this drug:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store tablets or capsules in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the drug to break down.
• Keep liquid and suppository forms of this drug from freezing.
• Do not keep outdated drug or drug no longer needed. Be sure that any discarded drug is out of the reach of children.