Anesthetics, General - Systemic
Anesthetics, General *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information
Before Using This Medication
In deciding to using a medication, the chance of taking the drug must be
weighed against the good it will do. This is a decision you
will make. For general anesthetics, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to barbiturates or general anesthetics. Also tell your health
care professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Pregnancy care
-
For barbiturate anesthetics - methohexital and
thiopental
Methohexital has not been studied in pregnant women.
However, it has not been shown to cause birth defects or other problems in
animal studies. Studies on effects in pregnancy with thiopental have not been
done in either humans or pets. However, use of barbiturate anesthetics
during pregnancy may effect the nervous system in the fetus.
-
For etomidate
Etomidate has not
been studied in pregnant women. Although studies in pets have not shown
etomidate to cause birth defects, it has been shown to cause other unwanted
effects in the animal fetus when given in doses usually many times the human
dose.
-
For inhalation anesthetics - enflurane, halothane,
isoflurane, methoxyflurane and nitrous oxide
Enflurane, halothane,
isoflurane, methoxyflurane and nitrous oxide have not been studied in pregnant
women. However, studies in pets have shown that inhalation anesthetics
may cause birth defects or other harm to the fetus.
When using as an anesthetic for an abortion, enflurane, halothane, or isoflurane
may cause increased bleeding.
When using in small doses to relieve pain during labor and delivery, halothane
may slow delivery and increase bleeding in the mother after the baby is born.
These effects do not occur with small doses of enflurane, isoflurane, or methoxyflurane.
However, they may occur with large doses of these anesthetics.
-
For ketamine
Ketamine has not been
studied in pregnant women. Studies in pets have not shown that ketamine
causes birth defects, but it has causing damage to certain tissues when given
in large amounts for a long period of time.
-
For propofol
Propofol has not been
studied in pregnant women. Although studies in pets have not shown propofol
to cause birth defects, it has been shown to cause deaths in nursing mothers
and their offspring when given in doses usually many times the human dose.
General anesthetics may cause unwanted effects, such as drowsiness, in
the newborn baby if large amounts are given to the mother during labor and
delivery.
Breast-feeding problem
Barbiturate anesthetics - methohexital and thiopental,
halothane and propofol pass into the breast milk. However, general anesthetics
have not been reported to cause problems in nursing babies.
Use for Children
Anesthetics given by inhalation and ketamine have
been tested in child and have not been shown to cause various side effects
or problems in child than they do in adults.Although there is no special info comparing use of etomidate in
children with use in other age groups, this drug is not expected to cause
various side effects or problems in child than it does in adults.
Although there is no special info comparing use of thiopental aplaying
intravenously in child with use in other age groups, using thiopental intravenously
in child is not expected to cause various side effects or problems in
children than it does in adults.
Propofol has been tested in child to produce loss of consciousness before
and during surgery. It has not been shown to cause various side effects
or problems in child than it does in adults. Propofol must not be using
in critically ill children to help the children withstand the stress of being
in the intensive care unit. Some critically ill children have developed problems
with their body chemistries after receiving propofol and a few children have
died as a result of this. It is not known if propofol or the severe illnesses
of the children causing this problem.
Elderly care
Elderly people are especially sensitive to the effects
of the barbiturate anesthetics - methohexital and thiopental, etomidate, propofol,
and anesthetics given by inhalation. This may increase the risk of side
effects.Ketamine has not been shown to cause various side effects or problems
in elderly people than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are receiving
general anesthetics, it is especially important that your health care professional
know if you are taking any other drug
, including
any of the following:
-
“Street” drugs, such as amphetamines - “uppers”,
barbiturates - “downers”, cocaine, marijuana, phencyclidine - PCP
or “angel dust” and heroin or other narcotics Serious,
possibly fatal, side effects may occur if your family doctor or dentist gives
you an anesthetic without knowing that you have taken another drug
Other Information for using
The presence of other medical
problems may effect the use of general anesthetics. Make sure you tell your
family doctor if you have any other medical problems, especially:
-
Malignant hyperthermia, during or shortly after receiving an anesthetic
- history of, or family history of. Signs of malignant hyperthermia include
very high fever, fast and irregular heartbeat, muscle spasms or tightness,
and breathing problems This side effect may occur again
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