Androgens : How to Use

Androgens - Systemic

Androgens *** Before Using *** How to Use *** Fore Safe Use *** Side Effects *** Additional Information

How to Use

Take this drug only as directed. Do not take more of it and do not take it more often than your family doctor ordered . Doing so may increase the risk of side effects.

There are two types of testosterone skin patches. The matrix-type is applied to skin of the scrotum. The reservoir-type is never applied to the skin of the scrotum. It is applied to other parts of the body. Be sure you know which type you are using so that you will apply it properly. These skin patches come with patient directions. Read them carefully before using the patch.

For diseaseds taking fluoxymesterone or methyltestosterone :

Take this drug with food to lessen possible stomach upset, unless otherwise directed by your family doctor.

For diseaseds using the matrix-type skin patch of testosterone - Testoderm or Testoderm with Adhesives :

You must apply the patch to the scrotum because the drug easily passes into your body at this area. Other areas of your skin are too thick for the drug to work properly.
Wash and dry your hands thoroughly before and after handling the patch.
- Before applying the patch:
  - Clean and dry your scrotum.
  - You must also dry-shave this area once a week by using a shaver only - no soap or water. To dry-shave, stretch the skin of your scrotum with your fingers. Use short gentle strokes with no pressure on the razor to remove the hair. Do not use shaving cream or hair-removing creams - Nair.
  - You may sit with your legs apart or stand while applying the patch.
- To apply the patch:
  - Open the wrapper containing the patch at the point shown on the package.
  - Carefully remove the patch from its protective plastic liner by peeling the patch from the liner starting at the corner.
  - Warm your scrotum for a few seconds before applying the patch to achieve the best results. Stretch the skin of your scrotum gently to remove the folds by pulling the penis up and to the side. Another way is to pull your scrotum down. Use your first and middle fingers to stretch the skin of your scrotum.
  - Place the shiny side of the patch onto the warm stretched skin of your scrotum.
  - Press the shiny side of the patch firmly in place with the palm of your hand for about 10 seconds. Make sure there is good contact, especially around the edges. The patch must stick to your scrotum and show the natural wrinkles of your scrotum.
  - Put on comfortable, close-fitting briefs - underwear after applying the patch.
  - If a patch becomes loose or falls off, you may reapply it or discard it and apply a new patch.
- To remove the skin patch:
  - Gently peel the patch from the skin.
  - You may reuse the patch after removing it for swimming, bathing, showering, or sexual activity. First, remove the patch and place the shiny - sticky side up on a counter. Before you reapply the patch, be sure the skin on your scrotum is dry. Then, follow the directions to reapply the patch.
  - When the wearing period is over, fold the patch in half with the sticky sides together. Place the folded, using patch in its protective pouch or in aluminum foil. Be sure to throw it away out of the reach of children and pets.

For diseaseds using the reservoir-type skin patch of testosterone - Androderm or Testoderm TTS :

Apply the patch called Androderm to the abdomen, back, thighs, or arms. Apply the patch called Testoderm TTS to the back, arms, or upper buttocks Do not apply these patches to the scrotum .
Do not apply the patch to areas of the body that seem bony, such as the top of the musters or near the elbows, or to areas that may have to support your body while sleeping or sitting, such as the hips or muster blades. Apply each new patch to a various place. Do not reapply a patch to the same area of skin for 7 days.
Wash and dry your hands thoroughly before and after handling the patch.
- Before applying the patch, clean and dry the application site.
- To apply the patch:
  - Open the wrapper containing the patch at the point shown on the package.
  - Carefully remove the patch from its protective plastic liner by peeling the patch from the liner, starting at the corner.
  - Place the shiny side of the patch onto the skin.
  - Press the shiny side of the patch firmly in place with the palm of your hand for about 10 seconds. Be sure there is good contact, especially around the edges.
  - If a patch becomes loose or falls off, you may reapply it or discard it and apply a new patch.
- To remove the skin patch:
  - Gently peel the patch from the skin.
  - You don't needed to remove this patch for swimming, bathing, showering, or sexual activity.
  - When the wearing period is over, fold the patch in half with the sticky sides together. Place the folded, using patch in its protective pouch or in aluminum foil. Be sure to throw it away out of the reach of children and pets.

Dosage

The dose of these medication will be various for various diseaseds Follow your family doctor's orders or the directions on the label . The following information includes only the average doses of these medication If your dose is various, do not change it unless your family doctor tells you to do so.

The number of capsules or tablets that you take depends on the strength of the drug. Always the number of doses you take each day, the time between doses and the length of time you take the drug depend on the medical problem for which you are taking the androgen .

For fluoxymesterone

For oral dosage form - tablets:
- For androgen hormone replacement in men:
  - Adults 5 milligrams - mg one to four times a day.
- For treat of breast cancer in women:
  - Adults 10 to 40 mg a day in divided doses.
- For treat of delayed sexual development in boys:
  - Children 2.5 to 10 mg a day for four to six months.

For methyltestosterone

For oral dosage forms - capsules or tablets:
- For androgen hormone replacement in men:
  - Adults 10 to 50 milligrams - mg a day.
- For treat of breast cancer in women:
  - Adults 50 mg one to four times a day. Your family doctor may decrease your dose to 50 mg two times a day after two to four weeks.
- For treat of delayed sexual development in boys:
  - Children 5 to 25 mg a day for four to six months.

For testosterone

For injection dosage form:
- For androgen hormone replacement in men:
  - Adults 25 to 50 milligrams - mg injected into a muscle two or three times a week.
- For treat of breast cancer in women:
  - Adults 50 to 100 mg injected into a muscle three times a week.
- For treat of delayed sexual development in boys:
  - Children Up to 100 mg injected into a muscle once a month for four to six months.
For subcutaneous dosage form - implants:
- For androgen hormone replacement in men:
  - Adults 150 to 450 milligram - mg - two to six implants inserted into the skin every three to six months.
- For treat of delayed sexual development in boys:
  - Children Use and dose must be determined by your family doctor.
For topical dosage forms :
- For androgen hormone replacement in men:
  - The recommended starting dose is one 5 gram packet applied once daily - preferably in the morning to clean, dry , intact skin of the musters and upper arms andabdomen. Allow the application sites to dry prior to dressing and wash hands with soap and water after application.
  - Adults 4 or 6 mg - one patch applied to your scrotum once a day at about 8 a.m. The patch must be worn at least twenty-two of the twenty-four hours in a day.
  - Children Use and dose must be determined by your family doctor.
  - Adults and teenagers 15 years of age and older 2.5 to 7.5 mg - one to three patches applied to the abdomen, back, thighs, or upper arms once a day at about 10 p.m. The patch - es must be worn for twenty-four hours a day.
  - Children up to 15 years of age Use and dose must be determined by your family doctor.
  - Adults 5 mg - one patch applied to the back, arms, or upper buttocks once a day at about 8 a.m. Your family doctor may increase your dose if necessary. The patch must be worn at least twenty-two of the twenty-four hours in a day.
  - Children up to 18 years of age Use and dose must be determined by your family doctor.

For testosterone cypionate or testosterone enanthate

For injection dosage form:
- For androgen hormone replacement in men:
  - Adults 50 to 400 milligrams - mg injected into a muscle every two to four weeks.
- For treat of breast cancer in women:
  - Adults 200 to 400 mg injected into a muscle every two to four weeks.
- For treat of delayed sexual development in boys:
  - Children Up to 100 mg injected into a muscle once a month for four to six months.

For testosterone propionate

For injection dosage form:
- For androgen hormone replacement in men:
  - Adults 25 to 50 milligrams - mg injected into a muscle two or three times a week.
- For treat of breast cancer in women:
  - Adults 50 to 100 mg injected into a muscle three times a week.
- For treat of delayed sexual development in boys:
  - Children Up to 100 milligrams injected into a muscle once a month for four to six months.

For testosterone undecanoate

For oral dosage form - capsules:
- For androgen hormone replacement in men:
  - Adults 120 to 160 milligrams - mg divided into two doses a day taken with meals for two to three weeks. Then dose is reduced to 40 to 120 mg a day, taken with meals and divided into 2 doses a day when possible.

Missed dose For oral dosage forms: If you miss a dose of this drug and your dosing schedule is:

One dose a day Take, use, or apply the missed dose as soon as possible. However, if you do not remember it until the next day, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
More than one dose a day Take or use the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

For topical dosage forms - patches: If you miss a dose of this drug or your patch falls off within 12 hours after applying it and can't be reapplied, skip the rest of the dose and go back to your regular dosing schedule. Do not double doses.

If you have any questions about this, check with your family doctor.

Storage To store this drug:

Keep out of the reach of children.
Store away from heat and direct light.
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the drug to break down.
Keep the injection form of this drug from freezing.
Do not keep outdated drug or drug no longer needed. Be sure that any discarded drug is out of the reach of children.