Androgens and Estrogens - Systemic
Androgens and Estrogens *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For androgen and estrogen
combination products, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to androgens, anabolic steroids, or estrogens. Also tell
your health care professional if you are allergic to any other substances,
such as foods, preservatives, or dyes.
Pregnancy care
Estrogens - contained in this combination drug
are not recommended for use during pregnancy, since some estrogens have been
shown to cause serious birth defects. Some daughters of women who
took diethylstilbestrol - DES during pregnancy have developed reproductive
- genital tract problems and, rarely, cancer of the vagina anduterine
cervix when they reached childbearing age. Some sons of women who took DES
during pregnancy have developed urinary-genital tract problems.Androgens - contained in this combination drug must not be using during
pregnancy because they may cause male-like changes in a female baby.
Breast-feeding problem
Use of this drug is not recommended in nursing
mothers. Estrogens pass into the breast milk and their possible effect on
the baby is not known. It is not known if androgens pass into breast milk.
However androgens may cause unwanted effects in nursing babies such as too
early sexual development in males or male-like changes in females.
Elderly care
This drug has been tested and has not been shown
to cause various side effects or problems in older women than it does in
younger females.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
an androgen and estrogen combination product, it is especially important that
your health care professional know if you are taking any of the following:
-
Acetaminophen - Tylenol - with long-term, high-dose use
-
Amiodarone - Cordarone
-
Anabolic steroids - nandrolone " Anabolin ", oxandrolone "
Anavar ", oxymetholone " Anadrol ", stanozolol " Winstrol "
-
Anti-infectives by mouth or by injection - drug for infection
-
Antithyroid agents - drug for overactive thyroid
-
Carbamazepine - Tegretol
-
Carmustine - BiCNU
-
Chloroquine - Aralen
-
Dantrolene - Dantrium
-
Daunorubicin - Cerubidine
-
Disulfiram - Antabuse
-
Divalproex - Depakote
-
Etretinate - Tegison
-
Gold salts - drug for arthritis
-
Hydroxychloroquine - Plaquenil
-
Mercaptopurine - Purinethol
-
Methotrexate - Mexate
-
Methyldopa - Aldomet
-
Naltrexone - Trexan - with long-term, high-dose use
-
Phenothiazines - acetophenazine " Tindal ", chlorpromazine "
Thorazine ", fluphenazine " Prolixin ", mesoridazine " Serentil ",
perphenazine " Trilafon ", prochlorperazine " Compazine ", promazine
" Sparine ", promethazine " Phenergan ", thioridazine " Mellaril ",
trifluoperazine " Stelazine ", triflupromazine " Vesprin ", trimeprazine
" Temaril "
-
Phenytoin - Dilantin
-
Plicamycin - Mithracin
-
Valproic acid - Depakene Androgens, estrogens and all
of these medication can cause liver damage. Your family doctor may want you to have
extra blood tests that tell about your liver, while you are taking any of
these medication with an androgen and estrogen combination product.
-
Anticoagulants - blood thinners Androgens can cause an increased
effect of blood thinners, which could lead to uncontrolled or excessive bleeding
-
Cyclosporine - Sandimmune Estrogens can increase the
chance of toxic effects to the kidney or liver from cyclosporine because
estrogens can interfere with the body's ability to get the cyclosporine out
of the bloodstream as it normally would
Other Information for using
The presence of other medical
problems may effect the use of androgen and estrogen combination products.
Make sure you tell your family doctor if you have any other medical problems, especially:
-
Blood clots - or history of during previous estrogen therapy Estrogens
may worsen blood clots or cause new clots to form
-
Breast cancer - active or suspected Estrogens may cause growth
of the tum
-
Changes in vaginal bleeding of unknown causes Some irregular
vaginal bleeding is a sign that the lining of the uterus is growing too much
or is a sign of cancer of the uterus lining; estrogens may make these conditions
worse
-
Diabetes mellitus - sugar diabetes Androgens can decrease blood
sugar levels
-
Edema - swelling of feet or lower legs causing by retaining "keeping "
too much body water
-
Heart or circulation disease
-
Kidney disease
-
Liver disease Androgens can worsen these conditions because
androgens cause the body to retain extra fluid - keep too much body water.
Always heart or circulation disease can be worsened by androgens because androgens
may increase blood cholesterol levels
-
Endometriosis Estrogens may worsen endometriosis by causing
growth of endometriosis implants
-
Fibroid tumors of the uterus Estrogens may cause fibroid tumors
to increase in size
-
Gallbladder disease or gallstones - or history of There is
no clear evidence as to whether estrogens increase the risk of gallbladder
disease or gallstones
-
Jaundice - or history of during pregnancy Estrogens use may
worsen or cause jaundice in these diseaseds
-
Liver disease Toxic drug effects may occur in diseaseds with
liver disease because the body is not able to get this drug out of the
bloodstream as it normally would
-
Porphyria Estrogens can worsen porphyria
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