Amphotericin B Liposomal Complex - Systemic
Brand Names
AmBisome
Amphotericin B Liposomal Complex *** Before Using *** How to Use *** Side Effects
Before Using
In deciding to using a medication,
the problems of uses this drugs must be weighed against the good it will do.
This is a decision you will make. For amphotericin B liposomal
complex, the following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to amphotericin B liposomal complex. Also tell your health
care professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Pregnancy care
Amphotericin B liposomal complex has not been reported
to cause birth defects or other problems. However, studies in pets
have shown that amphotericin B liposomal complex causes the fetus to abort
and other problems. Before taking this drug, make sure your family doctor knows
if you are pregnant or if you may become pregnant.
Breast-feeding problem
It is not known whether amphotericin B liposomal
complex passes into breast milk. However, amphotericin B liposomal complex
is not recommended during breast-feeding, because it may cause unwanted effects
in nursing babies.
Use for Children
Appropriate studies performed to date have not demonstrated
pediatrics-specific problems that would limit the usefulness of amphotericin
B liposomal complex in child.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people. Although there is no special info
comparing use of amphotericin B liposomal complex in the elderly with use
in other age groups, this drug is not expected to cause various side
effects or problems in elderly people than it does in adults people.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are receiving
amphotericin B liposomal complex, it is especially important that your health
care professional know if you are taking any of the following:
-
Aminoglycosides - amikacin " Amikin ", gentamicin " Garamycin ",
kanamycin " Kantrex ", neomycin " Mycifradin ", netilmicin "
Netromycin ", streptomycin, tobramycin " Nebcin "
-
Cyclosporine - Sandimmune
-
Pentamidine - NebuPent, Pentam 300
-
Tacrolimus - Prograf Use of these medication with amphotericin
B liposomal complex may increase the risk of side effects effecting the kidneys
-
Antineoplastic agents - cancer drug Use of cancer medication
with amphotericin B liposomal complex may increase the risk of side effects
effecting the blood, kidneys and lungs
-
Atracurium - Tracrium
-
Gallamine - Flaxedil
-
Metocurine - Metubine Iodide
-
Pancuronium - Pavulon
-
Tubocurarine
-
Vecuronium - Norcuron Use of these medication with amphotericin
B liposomal complex may increase the side effects of medication
-
Corticosteroids - cortisone-like drug
-
Corticotropin - ACTH
-
Digitalis glycosides - heart drug Use of amphotericin B
liposomal complex with corticosteroids, corticotropin, or digitalis medication
- such as digoxin may cause changes in the blood that may increase the risk
of heart problems
Other Information for using
The presence of other medical
problems may effect the use of amphotericin B liposomal complex. Make sure
you tell your family doctor if you have any other medical problems, especially:
-
Blood transfusion Amphotericin B liposomal complex may cause
side effects effecting the lungs
-
Kidney disease Amphotericin B liposomal complex may make your
kidney problems worse
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