Allopurinol - Systemic
Brand Names
Aloprim, Zyloprim, Apo-Allopurinol, Purinol
Allopurinol *** Before Using *** How to Use *** Fore Safe Use *** Side Effects
Before Using
In deciding to using a medication,
the chance of taking the drug must be weighed against the good it will
do. This is a decision you will make. For allopurinol, the
following must be considered
Allergic reaction
Tell your family doctor if you have any unusual or
allergy to allopurinol. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy care
Although studies on birth defects have not been done
in pregnant women, allopurinol has not been reported to cause problems in
humans. In one study in mice, large amounts of allopurinol causing birth defects
and other unwanted effects. However, allopurinol did not cause birth defects
or other problems in rats or rabbits given doses up to 20 times the amount
usually given to humans.
Breast-feeding problem
Allopurinol passes into the breast milk. Mothers
who are taking this drug and who wish to breast-feed must discuss this
with their family doctor.
Use for Children
This drug has been tested in child and, in
effective doses, has not been shown to cause various side effects or problems
than it does in adults.
Elderly care
Many medication have not been studied specifically
in elderly people. Therefore, it may not be known whether they work exactly
the same way they do in adults people or if they cause various side effects
or problems in elderly people. There is no special info comparing use
of allopurinol in the elderly with use in other age groups.
Drug interactions
Although certain medication must not be using
together at all, in other cases two various medication may be using together
even if an interaction might occur. In these cases, your family doctor may want to
change the dose, or other precautions may be necessary. When you are taking
allopurinol, it is especially important that your family doctor and pharmacist know
if you are taking any of the following:
-
Anticoagulants - blood thinners Allopurinol may increase the
risk of bleeding; changes in the dose of the anticoagulant may be needed,
depending on blood test results
-
Azathioprine - Imuran
-
Mercaptopurine - Purinethol Allopurinol may cause higher
blood levels of azathioprine or mercaptopurine, leading to an increased risk
of serious side effects
Other Information for using
The presence of other medical
problems may effect the use of allopurinol. Make sure you tell your family doctor
if you have any other medical problems, especially:
-
Congestive heart disease
-
Diabetes mellitus - sugar diabetes
-
High blood pressure
-
Kidney disease There is an increased risk of severe allergic
reactions or other serious effects; a change in the dose of allopurinol may
be needed
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