Acetaminophen and Salicylates : Before Using

Acetaminophen and Salicylates - Systemic

Acetaminophen and Salicylates *** Before Using *** How to Use *** Fore Safe Use *** Side Effects

Before Using

If you are taking this drug without a prescription, carefully read and follow any precautions on the label. For acetaminophen and salicylate combinations, the following must be considered

Allergic reaction

Tell your family doctor if you have any unusual or allergy to acetaminophen, aspirin or other salicylates including methyl salicylate - oil of wintergreen, or to any of the following medication:

Diclofenac - Voltaren
Diflunisal - Dolobid
Etodolac - Lodine
Fenoprofen - Nalfon
Floctafenine - Idarac
Flurbiprofen, oral - Ansaid
Ibuprofen - Motrin
Indomethacin - Indocin
Ketoprofen - Orudis
Ketorolac - Toradol
Meclofenamate - Meclomen
Mefenamic acid - Ponstel
Nabumetone - Relafen
Naproxen - Naprosyn
Oxaprozin - Daypro
Phenylbutazone - Butazolidin
Piroxicam - Feldene
Sulindac - Clinoril
Tenoxicam - Mobiflex
Tiaprofenic acid - Surgam
Tolmetin - Tolectin

Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy care

For acetaminophen : Studies on birth defects have not been done. However, acetaminophen has not been reported to cause birth defects or other problems.
For aspirin : Studies have not shown that aspirin causes birth defects. However, aspirin has been shown to cause birth defects in pets.
Do not take aspirin during the last 3 months of pregnancy unless it has been ordered by your family doctor . Some reports have suggested that too much use of aspirin late in pregnancy may cause a decrease in the newborn's weight and possible death of the fetus or newborn infant. However, the mothers in these reports had been taking much larger amounts of aspirin than are usually recommended. Studies of mothers taking aspirin in the doses that are usually recommended did not show these unwanted effects. However, there is a risk that regular use of aspirin late in pregnancy may cause unwanted effects on the heart or blood flow in the fetus or newborn infant.
Use of aspirin during the last 2 weeks of pregnancy may cause bleeding problems in the fetus before or during delivery, or in the newborn infant. Always too much use of aspirin during the last 3 months of pregnancy may increase the length of pregnancy, prolong labor, cause other problems during delivery, or cause severe bleeding in the mother before, during, or after delivery.
For salicylamide : Studies on birth defects have not been done.
For caffeine : Studies have not shown that caffeine causes birth defects. However, use of large amounts of caffeine by the mother during pregnancy may cause problems with the heart rhythm of the fetus and may effect the growth of the fetus. Studies in pets have shown that caffeine causes birth defects when given in very large doses - amounts equal to the amount of caffeine in 12 to 24 cups of coffee a day.

Breast-feeding problem

For acetaminophen and for aspirin : Acetaminophen and aspirin pass into breast milk; however, they have not been reported to cause problems in nursing babies.
For caffeine : Caffeine - contained in some of these combination medication passes into breast milk in small amounts. Taking caffeine in the amounts present in these medication has not been reported to cause problems in nursing babies. However, studies have shown that babies may appear jittery and have trouble in sleeping when their mothers drink large amounts of caffeine-containing beverages. Therefore, breast-feeding mothers who use these medication probably must limit the amount of caffeine they take in from other medication or from beverages.

Use for Children

For acetaminophen : Acetaminophen has been tested in child and, in effective doses, has not been shown to cause various side effects or problems than it does in adults.
For aspirin and for salicylamide : Do not give a drug containing aspirin or salicylamide to a child with symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's family doctor . This is very important because aspirin may cause a serious illness called Reye's syndrome in child with fever causing by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the risk of side effects during treat.
For caffeine : There is no special info comparing use of caffeine in child younger than 12 years of age with use in other age groups. However, caffeine is not expected to cause various side effects or problems in child than it does in adults.

Adolescents Teenagers with fever or other symptoms of a virus infection, especially flu or chickenpox, must check with a family doctor before taking a drug containing aspirin or salicylamide . Aspirin and salicylamide may cause a serious illness called Reye's syndrome in teenagers with fever causing by a virus infection, especially flu or chickenpox.

Elderly care

Elderly people may be more likely than adults people to develop serious kidney problems if they take large amounts of these combination medication for a long time. Therefore, it is best that elderly people not take this drug for more than 5 days in a row unless they are under a family doctor's care.

For acetaminophen : Acetaminophen has been tested and, in effective doses, has not been shown to cause various side effects or problems in elderly people than it does in adults people.
For aspirin : People 60 years of age and older are especially sensitive to the effects of aspirin. This may increase the risk of side effects during treat.
For caffeine : Many medication have not been studied specifically in elderly people. Therefore, it may not be known whether they work exactly the same way they do in adults people or if they cause various side effects or problems in elderly people. There is no specific information comparing use of caffeine in the elderly with use in other age groups.

Drug interactions

Although certain medication must not be using together at all, in other cases two various medication may be using together even if an interaction might occur. In these cases, your family doctor may want to change the dose, or other precautions may be necessary. When you are taking an acetaminophen and salicylate combination, it is especially important that your health care professional know if you are taking any of the following:

Anticoagulants - blood thinners
Carbenicillin by injection - Geopen
Cefamandole - Mandol
Cefoperazone - Cefobid
Cefotetan - Cefotan
Dipyridamole - Persantine
Divalproex - Depakote
Heparin
Inflammation or pain drug, except narcotics,
Pentoxifylline - Trental
Plicamycin - Mithracin
Ticarcillin - Ticar
Valproic acid - Depakene Taking these medication together with aspirin - present in some of these combination medication may increase the risk of serious bleeding

Antidiabetics, oral - diabetes drug you take by mouth Aspirin - present in some of these combination medication may increase the effects of the antidiabetic drug; a change in dose may be needed if aspirin is taken regularly

Ciprofloxacin - Cipro
Enoxacin - Penetrex
Itraconazole - Sporanox
Ketoconazole - Nizoral
Lomefloxacin - Maxaquin
Norfloxacin - Noroxin
Ofloxacin - Floxin
Tetracyclines - drug for infection, taken by mouth Antacids - present in buffered forms of acetaminophen and salicylate combination medication can keep these other medication from help you if the medication are taken too closely together

Methotrexate - Mexate Taking aspirin - present in some of these combination medication together with methotrexate may increase the risk of serious side effects

Probenecid - Benemid Aspirin - present in some of these combination medication can keep probenecid from help you for treating gout

Sulfinpyrazone - Anturane Aspirin - present in some of these combination medication can keep sulfinpyrazone from help you for treating gout; also, taking aspirin together with sulfinpyrazone may increase the risk of bleeding

Urinary alkalizers - drug that makes the urine less acid, such as acetazolamide " Diamox ", calcium- andmagnesium-containing antacids, dichlorphenamide " Daranide ", methazolamide " Neptazane ", potassium or sodium citrate andcitric acid, sodium bicarbonate "baking soda " These medication may make aspirin - present in some of these combination medication less effective by causing it to be removed from the body more quickly

Other Information for using

The presence of other medical problems may effect the use of acetaminophen and salicylate combinations. Make sure you tell your family doctor if you have any other medical problems, especially:

Alcohol abuse
Asthma, allergies and nasal polyps - history of
Hepatitis or other liver disease
Kidney disease The risk of serious side effects may be increased

Anemia
Stomach ulcer or other stomach problems Aspirin - present in some of these combination medication may make these conditions worse

Gout Aspirin - present in some of these combination medication can make this condition worse and can also lessen the effects of some medication using to treat gout

Heart disease Caffeine - present in some of these combination medication can make your condition worse

Hemophilia or other bleeding problems Aspirin - present in some of these combination medication increases the risk of serious bleeding